COX17 and PPBP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COX17	PPBP
Description		cytochrome c oxidase copper chaperone COX17	pro-platelet basic protein
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Intermembrane Space	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Tertiary Granule Lumen
	Molecular Function	Copper Ion Binding Protein Binding Copper Chaperone Activity Cuprous Ion Binding	Glucose Transmembrane Transporter Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Copper Ion Transport Brain Development Heart Development Positive Regulation Of Cell Proliferation Mitochondrial Respiratory Chain Complex IV Assembly Positive Regulation Of Cytochrome-c Oxidase Activity	Platelet Degranulation Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Leukocyte Chemotaxis Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Glucose Transmembrane Transport
Pathways		Mitochondrial protein import	Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation
Drugs			Ethanesulfonic Acid Copper
Diseases
GWAS			Metabolite levels ( 22916037)
Interacting Genes		10 interacting genes: COPS6 EEF1A1 ERG28 HADHB KATNAL1 LRIF1 PPBP RBM48 TP53 UNC119	20 interacting genes: CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4
Entrez ID		10063	5473
HPRD ID		05314	07171
Ensembl ID		ENSG00000138495	ENSG00000163736
Uniprot IDs		Q14061	P02775
PDB IDs		2L0Y 2LGQ 2RN9 2RNB	1F9P 1NAP 1TVX
Enriched GO Terms of Interacting Partners?
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