CHAF1A and MBD1

Number of citations of the paper that reports this interaction (PubMedID 17066076)
30

Data Source:
HPRD (two hybrid, in vivo)

		CHAF1A	MBD1
Description		chromatin assembly factor 1 subunit A	methyl-CpG binding domain protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Protein-containing Complex CAF-1 Complex	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Chromatin Binding Protein Binding Identical Protein Binding Unfolded Protein Binding Chromo Shadow Domain Binding	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Negative Regulation Of Transcription By RNA Polymerase II Methylation-dependent Chromatin Silencing Transcription By RNA Polymerase II Heart Development Aging Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation
Pathways			SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red cell distribution width ( 27863252 28957414)	Chronic lymphocytic leukemia ( 28165464)
Interacting Genes		39 interacting genes: ANP32A ANP32B ASF1A ASF1B BLM CBX1 CBX5 CDC7 CDK2 CHAF1B CREBBP DBF4 DDX41 H3-4 H3C6 HMGB2 LZTR1 MBD1 MSH6 PABPC1 PCBD2 PCNA RBFOX2 REL SET SPOP SUMO1 SUMO2 SUMO3 TCERG1 TCF4 TRIM28 XRCC5 XRCC6 YWHAB YWHAE YWHAG YWHAQ ZNF408	25 interacting genes: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SP1 SUV39H1 TENM1 ZNF512B
Entrez ID		10036	4152
HPRD ID		03148	01133
Ensembl ID		ENSG00000167670	ENSG00000141644
Uniprot IDs		Q13111	A8K654 B4DI41 B4DUR3 Q9UIS9
PDB IDs			1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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