HTR2B

Description		5-hydroxytryptamine receptor 2B
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GO Annotations	Cellular Component	Cell Nucleoplasm Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Dendrite Synapse
	Molecular Function	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity GTPase Activator Activity Protein Binding Drug Binding Neurotransmitter Receptor Activity Serotonin Binding
	Biological Process	Neural Crest Cell Migration Positive Regulation Of Cytokine Production Positive Regulation Of Endothelial Cell Proliferation G Protein-coupled Receptor Internalization Heart Morphogenesis Cardiac Muscle Hypertrophy Cellular Calcium Ion Homeostasis G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Behavior Positive Regulation Of Cell Proliferation Negative Regulation Of Autophagy Positive Regulation Of Phosphatidylinositol Biosynthetic Process Neural Crest Cell Differentiation Phosphatidylinositol 3-kinase Signaling Intestine Smooth Muscle Contraction Phosphorylation Calcium-mediated Signaling CGMP-mediated Signaling Vasoconstriction Response To Drug Negative Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Embryonic Morphogenesis Positive Regulation Of Cytokine Secretion Regulation Of Behavior Positive Regulation Of Nitric-oxide Synthase Activity Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Cell Division Negative Regulation Of Cell Death ERK1 And ERK2 Cascade Positive Regulation Of ERK1 And ERK2 Cascade Protein Kinase C Signaling Cellular Response To Temperature Stimulus G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways		Serotonin receptors G alpha (q) signalling events
Drugs		Eletriptan Methysergide Cabergoline Ropinirole Dihydroergotamine Olanzapine Methylergometrine Mirtazapine Pramipexole Chlorpromazine Triflupromazine Amoxapine Fenfluramine Lisuride Ergotamine Apomorphine Minaprine Ergoloid mesylate Tegaserod Doxepin Pergolide Bromocriptine Ketamine Chlorprothixene Clomipramine Yohimbine Midomafetamine Lysergic Acid Diethylamide OPC-28326 Epicept NP-1 Cariprazine Mianserin Asenapine Esmirtazapine Setiptiline Tiapride
Diseases
GWAS		Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		4 interacting genes: GNA11 GNAQ LNX1 SNTA1
Entrez ID		3357
HPRD ID		03077
Ensembl ID		ENSG00000135914
Uniprot IDs		P41595
PDB IDs		4IB4 4NC3 5TUD 5TVN 6DRX 6DRY 6DRZ 6DS0
Enriched GO Terms of Interacting Partners?
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