CDC25C and CDS1

Number of citations of the paper that reports this interaction (PMID 10681541)
95

Data Source:
BioGRID (enzymatic study)

		CDC25C	CDS1
Gene Name		cell division cycle 25C	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding WW Domain Binding	Diacylglycerol Cholinephosphotransferase Activity Phosphatidate Cytidylyltransferase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Spermatogenesis Cell Proliferation Viral Process Peptidyl-tyrosine Dephosphorylation Cell Division Regulation Of Cell Cycle	Phospholipid Metabolic Process CDP-choline Pathway Phosphatidylinositol Biosynthetic Process Signal Transduction Phototransduction CDP-diacylglycerol Biosynthetic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways		Cyclin A/B1 associated events during G2/M transition G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex G2/M Transition Cell Cycle Checkpoints Mitotic G2-G2/M phases Cyclin B2 mediated events Polo-like kinase mediated events Cell Cycle, Mitotic	Metabolism of lipids and lipoproteins Synthesis of PI Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: BRSK1 BRSK2 CCNA2 CCNB1 CDK1 CDK2 CDS1 CHEK1 CHEK2 HRAS LCK LZTS1 MAPK1 MAPK14 MAPK3 MAPK9 MARK3 NEDD4 PCNA PIN1 PKN1 PLK1 PLK3 SRC TP53 YWHAB YWHAH YWHAQ YWHAZ	1 interactors: CDC25C
Entrez ID		995	1040
HPRD ID		01146	11944
Ensembl ID		ENSG00000158402	ENSG00000163624
Uniprot IDs		P30307	Q92903
PDB IDs		3BZI 3OP3
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Cell Cycle Phosphorylation Response To Stress Cell Cycle Checkpoint Apoptotic Process G2/M Transition Of Mitotic Cell Cycle Programmed Cell Death Cell Death Death Protein Phosphorylation Regulation Of Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Metabolic Process Response To Abiotic Stimulus Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Transport Negative Regulation Of Mitotic Cell Cycle Ras Protein Signal Transduction Phosphate-containing Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Regulation Of Protein Phosphorylation Cellular Response To Stimulus Positive Regulation Of Phosphorylation Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Signal Transduction Cell Aging Regulation Of Cellular Localization Regulation Of Phosphorylation Regulation Of Cellular Component Organization Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Cellular Protein Modification Process
Tagcloud ?		acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc	adopt assemble cdp cycling determines dg droplets esters fission fundamental grow kennedy lifestyle machinery organelles packaging phosphatidic recruit reliant resident rewires route specialized sterol sterols stored triacylglycerol triacylglycerols unusual
Tagcloud (Difference) ?		acetyltransferase acetyltransferases aiding ancient assembled box caf ccaat collagen disrupted facilitating gcn5 heterodimers histocompatibility lipase nf pivotal possess r2 reductase ribonucleotide transactivation transfections ubiquitous y ya yb yc	adopt assemble cdp cycling determines dg droplets esters fission fundamental grow kennedy lifestyle machinery organelles packaging phosphatidic recruit reliant resident rewires route specialized sterol sterols stored triacylglycerol triacylglycerols unusual
Tagcloud (Intersection) ?