FEZ1 and SCOC

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FEZ1	SCOC
Gene Name		fasciculation and elongation protein zeta 1 (zygin I)	short coiled-coil protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite	Golgi Membrane Endosome Trans-Golgi Network Cytosol
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus	Positive Regulation Of Macroautophagy
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	8 interactors: ARL1 FEZ1 FEZ2 ITSN1 KRT40 MAPK8 SCHIP1 TCF4
Entrez ID		9638	60592
HPRD ID		09212	18027
Ensembl ID		ENSG00000149557	ENSG00000153130
Uniprot IDs		Q99689	Q9UIL1
PDB IDs			4BWD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated	Response To External Stimulus Axon Guidance Organelle Localization Positive Regulation Of Protein Kinase B Signaling Axonogenesis Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Chemotaxis Generation Of Neurons Regulation Of Protein Kinase B Signaling Positive Regulation Of Cell Death Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Neuron Projection Morphogenesis Neurogenesis Regulation Of Protein Binding Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Cell Morphogenesis Involved In Differentiation Cell Development Maintenance Of DNA Repeat Elements Neuron Projection Development JUN Phosphorylation Cell Projection Morphogenesis Establishment Of Localization In Cell Cell Part Morphogenesis Vesicle Localization Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Deacetylase Activity Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Apoptotic Process Neurotrophin Signaling Pathway Negative Regulation Of Programmed Cell Death Embryonic Genitalia Morphogenesis Neuron Development Positive Regulation Of Intracellular Transport Negative Regulation Of Cell Death Positive Regulation Of Determination Of Dorsal Identity Myoblast Fate Commitment Nervous System Development Regulation Of Binding Cellular Response To Stimulus Positive Regulation Of Hydrolase Activity Secretory Granule Localization Cell Morphogenesis Ossification
Tagcloud ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?