CREB5 and KRTAP4-2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CREB5	KRTAP4-2
Gene Name		cAMP responsive element binding protein 5	keratin associated protein 4-2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Keratin Filament
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Adipose Tissue Development
Pathways
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder ( 18839057) Crohn's disease ( 23128233) Diabetic retinopathy ( 21441570)
Protein-Protein Interactions		37 interactors: ADAMTSL4 ATF2 COL8A1 EFEMP2 FOS FOSL1 FOSL2 JUN KIFC3 KRT15 KRT40 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 KRTAP9-4 MDFI MGAT5B MTUS2 NOTCH2NL RBPMS RGS20 RIMBP3 SPRY1 SPRY2 TRAF2 TRIM23 TRIP6 TSGA10	72 interactors: ADAMTSL4 ALDH3B1 AMOTL2 AQP1 ATG9A BYSL C19orf66 CHIC2 CHRD CRCT1 CREB5 DLGAP2 DOCK2 FAM74A4 GLRX3 GNMT HOXA1 HPCAL1 HSD3B7 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LASP1 LCE1B LCE2A LCE3C LCE3E LCE4A LNX1 MEOX2 NLK NOTCH2NL NR1D2 NUFIP2 OTX1 PDE9A PGLS PIN1 PLSCR1 POM121L8P PRKAB2 PRKAG1 PSMA6 PVRL3 RASSF5 RGS20 SLC23A1 SLC25A10 SPATA24 SPATA3 SPRY1 TCEANC TINAGL1 TRIM42 TXNDC5 TYRO3 WDYHV1 ZBTB24 ZNF124 ZNF20 ZNF417 ZNF559 ZNF581
Entrez ID		9586	85291
HPRD ID		09896	13944
Ensembl ID		ENSG00000146592	ENSG00000244537
Uniprot IDs		Q02930	Q9BYR5
PDB IDs
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Response To Corticosterone Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Response To CAMP Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Response To Mineralocorticoid Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Organophosphorus Response To Progesterone Regulation Of Neurotrophin TRK Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Purine-containing Compound Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Innate Immune Response Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Response To Reactive Oxygen Species MyD88-dependent Toll-like Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Response To Mechanical Stimulus MAPK Cascade Regulation Of Innate Immune Response Response To Gravity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Organ Morphogenesis Branch Elongation Of An Epithelium Regulation Of Protein Phosphorylation Learning Cellular Response To Inorganic Substance Response To Glucocorticoid Negative Regulation Of GTPase Activity Response To Corticosteroid Axis Elongation Response To Oxidative Stress Regulation Of Protein Import Into Nucleus Tissue Development Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	Keratinization Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Transcription, DNA-templated Epithelium Development Skin Development RNA Biosynthetic Process Organ Development Tissue Development Transepithelial Transport Cellular Process Cellular Nitrogen Compound Metabolic Process Gene Expression Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Apoptotic Cell Clearance BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Abducens Nerve Formation Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Optokinetic Behavior Transepithelial L-ascorbic Acid Transport Organic Anion Transport
Tagcloud ?		additionally biomarkers carcinoid col4a3 differentially expressions favorable fc fcs meaningful member mirnas mrnas mutated neoplasms neuroendocrine overlapped pcts predicted prediction profiling ptprb repeated tools top tp53 uncovered warrant yielded
Tagcloud (Difference) ?		additionally biomarkers carcinoid col4a3 differentially expressions favorable fc fcs meaningful member mirnas mrnas mutated neoplasms neuroendocrine overlapped pcts predicted prediction profiling ptprb repeated tools top tp53 uncovered warrant yielded
Tagcloud (Intersection) ?