CTDP1 and WDR77

Number of citations of the paper that reports this interaction (PMID 15670829)
17

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, biochemical)
HPRD (in vivo)

		CTDP1	WDR77
Gene Name		CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	WD repeat domain 77
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Spindle Actin Cytoskeleton Midbody Spindle Midzone	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Methylosome
	Molecular Function	DNA-directed RNA Polymerase Activity CTD Phosphatase Activity	Protein Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Dephosphorylation Exit From Mitosis Gene Expression Viral Process Positive Regulation Of Viral Transcription Cell Division	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Gene Expression NcRNA Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Abortive elongation of HIV-1 transcript in the absence of Tat HIV Infection Formation of the Early Elongation Complex Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation	Chromatin modifying enzymes snRNP Assembly Chromatin organization Metabolism of non-coding RNA RMTs methylate histone arginines
Drugs
Diseases
GWAS		Schizophrenia ( 23212062)
Protein-Protein Interactions		42 interactors: CDK7 CDK8 CDK9 CSNK2A1 CSNK2A2 CSNK2B E2F1 ELP2 ELP3 ERH GTF2F1 HIST1H4A HIST2H2AC INTS1 INTS3 INTS6 INTS7 INTS8 MED1 MED14 MED15 MED16 MED17 MED23 MED24 MED25 MED26 MED4 MED6 MED7 MED8 NDRG2 POLR2A POLR2B PRKDC PRMT5 SNRNP70 SNRPB STK38 TCEA1 UPP1 WDR77	35 interactors: AQR BAG2 COPRS CTDP1 GPKOW HIST2H2AB HNRNPM LSM3 NKX3-1 PCBP2 PPIL1 PPP1R8 PQBP1 PRMT5 QKI RBM5 SAP30BP SF1 SF3A1 SF3B4 SMAD1 SMYD1 SNRPB SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SUZ12 THOC1 TOE1 YWHAB YWHAQ ZNF207
Entrez ID		9150	79084
HPRD ID		05377	14387
Ensembl ID		ENSG00000060069	ENSG00000116455
Uniprot IDs		Q9Y5B0	B4DP38 Q9BQA1
PDB IDs		1J2X 1ONV 2K7L	4GQB
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Androgen Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-templated Transcription, Elongation Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Viral Transcription NcRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process SnRNA Processing Regulation Of Viral Transcription Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Process Stem Cell Maintenance SnRNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Checkpoint MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Stem Cell Development Positive Regulation Of Metabolic Process 7-methylguanosine MRNA Capping Regulation Of Viral Process	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Spliceosomal Complex Assembly Transcription, DNA-templated Histone MRNA Metabolic Process RNA Biosynthetic Process Cellular Metabolic Process Cellular Component Assembly NcRNA Metabolic Process Termination Of RNA Polymerase II Transcription DNA-templated Transcription, Termination MRNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA 3'-end Processing MRNA 3'-splice Site Recognition Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Histone Methylation Regulation Of RNA Metabolic Process MRNA Splice Site Selection Biosynthetic Process Histone H4-R3 Methylation Protein Methylation Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Alternative MRNA Splicing, Via Spliceosome Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Splicing Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Difference) ?		13q14 18qtel 1p32 3p14 3q21 4q11 4q24 5p13 5p15 5ptel 8p23 9qtel c84c11 cgh d1s427 d5s23 d8s504 d9s325 dab2 dxs7132 faf1 fhit genosensor imbalances q12 rbp1 rbp2 shgc xq12	androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 ncoa4 p44 pca promotion spliced suppressive switch switches tblr1 versions
Tagcloud (Intersection) ?