USP13 and FNBP1L

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP13	FNBP1L
Gene Name		ubiquitin specific peptidase 13 (isopeptidase T-3)	formin binding protein 1-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome	Cytoplasm Cytoskeleton Plasma Membrane Cell Cortex Cytoplasmic Membrane-bounded Vesicle Extracellular Vesicular Exosome
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Omega Peptidase Activity Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding	Protein Binding Lipid Binding
	Biological Process	Regulation Of Transcription, DNA-templated Autophagy Cell Proliferation Regulation Of Autophagy Melanocyte Differentiation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Proteasomal Protein Catabolic Process Protein K63-linked Deubiquitination	Membrane Budding Autophagy Membrane Invagination Vesicle Organization Vesicle Transport Along Actin Filament Cilium Assembly Positive Regulation Of Filopodium Assembly Clathrin-mediated Endocytosis Membrane Tubulation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: DVL1 FNBP1L FUNDC2 LAPTM5 MRPL20 MYO15A PTEN SIAH2 SPRR2C TRIM55 TRIM63 UBC	5 interactors: ACP1 DNM2 SGSM2 USP13 WASL
Entrez ID		8975	54874
HPRD ID		04666	12317
Ensembl ID		ENSG00000058056	ENSG00000137942
Uniprot IDs		Q92995	B4DSI7 J3QSS4 Q5T0N5
PDB IDs		2L80 2LBC
Enriched GO Terms of Interacting Partners?		Prepulse Inhibition Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Catabolic Process Startle Response Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Ubiquitination Positive Regulation Of Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Social Behavior Regulation Of Proteolysis Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cell Projection Morphogenesis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Membrane Organization Cell Part Morphogenesis Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Metabolic Process Positive Regulation Of Ligase Activity Regulation Of Protein Catabolic Process Dendrite Morphogenesis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Canonical Wnt Signaling Pathway Activation Of APC-Cdc20 Complex Activity Postsynaptic Density Assembly Negative Regulation Of Presynaptic Membrane Organization Inner Ear Morphogenesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Cell Morphogenesis Negative Regulation Of Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell Projection Organization Ubiquitin-dependent Protein Catabolic Process Cell Projection Organization Convergent Extension Involved In Neural Plate Elongation Negative Regulation Of Dendritic Spine Morphogenesis Vesicle Transport Along Actin Filament Modification-dependent Protein Catabolic Process	Negative Regulation Of Membrane Tubulation Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Nitric-oxide Synthase Activity Regulation Of Oxidoreductase Activity Reactive Oxygen Species Metabolic Process Vesicle Transport Along Actin Filament Late Endosome To Golgi Transport Establishment Of Vesicle Localization Vesicle Localization Positive Regulation Of Clathrin-mediated Endocytosis Golgi Vesicle Transport Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Establishment Of Organelle Localization Vesicle-mediated Transport Regulation Of Clathrin-mediated Endocytosis Organelle Localization Cellular Protein Complex Localization Protein K63-linked Deubiquitination Regulation Of Cell Projection Organization Protein Complex Localization Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Tagcloud ?		adamts2 aldh1a3 alpl2 apod cabin1 casp10 cdh16 classes classifier clgn covering crabp1 dataset datasets enrichments follicular gnas hmgb2 krthb5 microfollicular nr2f2 nras pax8 predictions sdha separating similarities subclasses timp1
Tagcloud (Difference) ?		adamts2 aldh1a3 alpl2 apod cabin1 casp10 cdh16 classes classifier clgn covering crabp1 dataset datasets enrichments follicular gnas hmgb2 krthb5 microfollicular nr2f2 nras pax8 predictions sdha separating similarities subclasses timp1
Tagcloud (Intersection) ?