BCL10 and SLC20A1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BCL10	SLC20A1
Gene Name		B-cell CLL/lymphoma 10	solute carrier family 20 (phosphate transporter), member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Nucleus Cytoplasm Lysosome Cytosol Cytoplasmic Microtubule Plasma Membrane CBM Complex T Cell Receptor Complex Protein Complex Membrane Raft Lipopolysaccharide Receptor Complex Perinuclear Region Of Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Protease Binding Transcription Coactivator Activity Protein Binding Protein C-terminus Binding Transcription Factor Binding Kinase Activator Activity Enzyme Binding Kinase Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Protein Kinase B Binding Protein Self-association NF-kappaB Binding	Signal Transducer Activity Receptor Activity Inorganic Phosphate Transmembrane Transporter Activity High-affinity Inorganic Phosphate:sodium Symporter Activity Sodium:phosphate Symporter Activity
	Biological Process	B Cell Apoptotic Process Neural Tube Closure Toll-like Receptor Signaling Pathway Response To Molecule Of Bacterial Origin Adaptive Immune Response Negative Regulation Of Mature B Cell Apoptotic Process Cellular Defense Response Cell Death Response To Fungus Immunoglobulin Mediated Immune Response Positive Regulation Of Protein Ubiquitination Response To Food Positive Regulation Of Mast Cell Cytokine Production Fc-epsilon Receptor Signaling Pathway Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Positive Regulation Of Phosphorylation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Innate Immune Response Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of Transcription, DNA-templated T Cell Receptor Signaling Pathway Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Oligomerization Protein Homooligomerization T Cell Apoptotic Process Cellular Response To Mechanical Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Phosphate-containing Compound Metabolic Process Transport Ion Transport Signal Transduction Phosphate Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Transmembrane Transport
Pathways		Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) TCR signaling FCERI mediated NF-kB activation Downstream TCR signaling Activation of NF-kappaB in B cells Fc epsilon receptor (FCERI) signaling Adaptive Immune System Innate Immune System	Sodium-coupled phosphate cotransporters Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AKT1 ATM BIRC3 C9orf89 CARD10 CARD11 CARD14 CARD9 CASP9 CDK9 CHUK IKBKB IKBKG IL15RA IRAK1 MALT1 MAP3K7 MIB2 NLRC4 PELI2 PRRG4 RIPK2 SLC20A1 SLC9A3R1 SOCS3 SRSF1 TLR4 TNFRSF10A TNFRSF1A TRADD TRAF2 UBC UBE2N UBE2V2 USHBP1	3 interactors: BCL10 MAPK6 RAPGEF1
Entrez ID		8915	6574
HPRD ID		04625	08846
Ensembl ID		ENSG00000142867	ENSG00000144136
Uniprot IDs		O95999	A7LNJ1 Q8WUM9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Activation Of Innate Immune Response Regulation Of Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Toll-like Receptor Signaling Pathway Regulation Of Cell Death Regulation Of Signaling Innate Immune Response Positive Regulation Of Protein Metabolic Process Regulation Of Immune Response Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway NIK/NF-kappaB Signaling Toll-like Receptor 2 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Immune System Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Defense Response Positive Regulation Of Immune Response Toll-like Receptor 9 Signaling Pathway Regulation Of NIK/NF-kappaB Signaling Signal Transduction Immune Response Positive Regulation Of Immune System Process Cell Surface Receptor Signaling Pathway	Positive Regulation Of Mast Cell Cytokine Production Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Mature B Cell Apoptotic Process Interleukin-6 Production Positive Regulation Of Interleukin-8 Biosynthetic Process B Cell Apoptotic Process Rap Protein Signal Transduction Negative Regulation Of B Cell Apoptotic Process Regulation Of Interleukin-8 Biosynthetic Process Nerve Growth Factor Signaling Pathway Positive Regulation Of Rap GTPase Activity T Cell Apoptotic Process Regulation Of B Cell Apoptotic Process Regulation Of Rap GTPase Activity Response To Food Cytokine Biosynthetic Process Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Regulation Of Rap Protein Signal Transduction Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Intracellular Signal Transduction Establishment Of Endothelial Barrier Cytokine Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Interleukin-8 Production Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Kinase B Signaling Response To Fungus Positive Regulation Of Hydrolase Activity Regulation Of T Cell Receptor Signaling Pathway Endothelial Cell Development Epithelium Development Platelet-derived Growth Factor Receptor Signaling Pathway Cellular Response To CAMP Positive Regulation Of Cytokine Production Involved In Immune Response Negative Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of Cellular Protein Metabolic Process Cellular Defense Response Negative Regulation Of Leukocyte Apoptotic Process Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Cell Junction Assembly Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Lymphocyte Apoptotic Process Positive Regulation Of Signal Transduction Activation Of MAPKK Activity Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Phosphorylation Cellular Response To Mechanical Stimulus
Tagcloud ?		adaptor assembly carma1 cbm clustering clusters connecting cytosolic effector engagement ensure ikappab ikappabalpha ikk incompletely inhibiting kappab malt1 nf p62 recruited requires signalosome signalosomes tak1 tcr transiently translocated triggers
Tagcloud (Difference) ?		adaptor assembly carma1 cbm clustering clusters connecting cytosolic effector engagement ensure ikappab ikappabalpha ikk incompletely inhibiting kappab malt1 nf p62 recruited requires signalosome signalosomes tak1 tcr transiently translocated triggers
Tagcloud (Intersection) ?