MCM3AP and ENY2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MCM3AP	ENY2
Gene Name		minichromosome maintenance complex component 3 associated protein	enhancer of yellow 2 homolog (Drosophila)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	SAGA Complex Nuclear Pore Transcription Export Complex 2 DUBm Complex
	Molecular Function	DNA Binding Transferase Activity, Transferring Acyl Groups	Transcription Coactivator Activity Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Immune System Process DNA Replication Protein Import Into Nucleus MRNA Transport	Chromatin Organization Transcription Elongation From RNA Polymerase II Promoter MRNA Export From Nucleus Protein Transport Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS		Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		19 interactors: APC CDC25A CDC42 CDC73 CLSTN1 CRMP1 ENY2 EP300 FAM118B MCM3 NUDT5 POLR2G RAC1 SMAD3 SMAD9 SUV39H2 TAF1D TMEM216 TSC22D1	2 interactors: APP MCM3AP
Entrez ID		8888	56943
HPRD ID		04483	13121
Ensembl ID		ENSG00000160294	ENSG00000120533
Uniprot IDs		O60318	Q9NPA8
PDB IDs		4DHX	4DHX
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cell-cell Junction Organization Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Anatomical Structure Morphogenesis Organelle Organization Regulation Of Nitrogen Compound Metabolic Process Cell Cycle DNA-templated Transcription, Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Pseudopodium Assembly Regulation Of Cell Cycle Wnt Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of MRNA 3'-end Processing Response To Hypoxia Positive Regulation Of Cell Death Chromosome Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of MRNA 3'-end Processing Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell Projection Assembly Epithelium Development Response To Abiotic Stimulus Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Positive Regulation Of Cell Adhesion Tissue Development Biosynthetic Process Histone Modification Stem Cell Maintenance Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Wnt Signaling Pathway Cell Development	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Establishment Of Localization In Cell Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth Immune System Process RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior
Tagcloud ?		adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey	adequate axillary classification classifier classifiers differentially enough etf1 fbx033 flj339115 flj33915 heterogeneity indicative infiltrated malignancy multiplex nodes osbpl parts predicting prognostic rps7 sets solely subdivides subgroup subtype usp38 validate
Tagcloud (Difference) ?		adenomatous arhgap causative cntn6 cnv cnvs ctnnb1 etiologically filtered focad german germline hsph1 kiaa1797 kif26b mining mutyh ngs nonrecurrent polyposis predispose predisposition prioritized silico stringent truncating uncover unexplained ybey	adequate axillary classification classifier classifiers differentially enough etf1 fbx033 flj339115 flj33915 heterogeneity indicative infiltrated malignancy multiplex nodes osbpl parts predicting prognostic rps7 sets solely subdivides subgroup subtype usp38 validate
Tagcloud (Intersection) ?