DEGS1 and NAGPA

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DEGS1	NAGPA
Gene Name		delta(4)-desaturase, sphingolipid 1	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane	Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Electron Carrier Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen	N-acetylglucosamine-1-phosphodiester Alpha-N-acetylglucosaminidase Activity
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Sphingolipid Metabolic Process Sphingolipid Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process	Carbohydrate Metabolic Process Cellular Protein Modification Process Protein Glycosylation Protein Targeting To Lysosome Lysosome Organization
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: EGFR NAGPA	5 interactors: AP2A1 DEGS1 EPS15 FURIN ZHX2
Entrez ID		8560	51172
HPRD ID		13133	12145
Ensembl ID		ENSG00000143753	ENSG00000103174
Uniprot IDs		O15121	Q9UK23
PDB IDs
Enriched GO Terms of Interacting Partners?		Alkanesulfonate Metabolic Process Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Activation Of Phospholipase A2 Activity Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Response To Hydroxyisoflavone Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Catenin Import Into Nucleus Protein Targeting To Lysosome Regulation Of Phospholipase A2 Activity Regulation Of Superoxide Anion Generation Protein Localization To Lysosome Magnesium Ion Homeostasis Cellular Response To Estradiol Stimulus Protein Insertion Into Membrane Astrocyte Development Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Protein Targeting To Vacuole Regulation Of Catenin Import Into Nucleus Cellular Response To Epidermal Growth Factor Stimulus Establishment Of Protein Localization To Vacuole Response To Epidermal Growth Factor Cellular Response To Estrogen Stimulus Cellular Response To Dexamethasone Stimulus Positive Regulation Of Vasoconstriction Positive Regulation Of Vasodilation Hydrogen Peroxide Metabolic Process Morphogenesis Of An Epithelial Fold Response To Dexamethasone Positive Regulation Of DNA Repair Tongue Development Regulation Of Nitric-oxide Synthase Activity Cellular Protein Localization Astrocyte Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Salivary Gland Morphogenesis Regulation Of Vasodilation Lysosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Salivary Gland Development Establishment Of Protein Localization Negative Regulation Of ERBB Signaling Pathway Activation Of Phospholipase C Activity Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus	Golgi To Endosome Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Post-Golgi Vesicle-mediated Transport Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nerve Growth Factor Production Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta1 Production Negative Regulation Of Receptor Catabolic Process Negative Regulation Of Hyaluronan Biosynthetic Process Endosomal Transport Nerve Growth Factor Processing Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Production Golgi Vesicle Transport Viral Protein Processing Positive Regulation Of Membrane Protein Ectodomain Proteolysis Peptidyl-glutamic Acid Carboxylation Signal Peptide Processing Virion Assembly Endocytic Recycling Viral Process Regulation Of Defense Response To Virus By Virus Establishment Of Localization In Cell Cellular Response To Growth Factor Stimulus Response To Growth Factor Peptide Biosynthetic Process Endocytosis Clathrin Coat Assembly Peptide Hormone Processing Clathrin-mediated Endocytosis Cytoplasmic Transport Cell Proliferation Cellular Localization
Tagcloud ?		adults cholesterol depth dyslipidemia english estimates excess german germany international interview lipoprotein lowering medication men persons prevalence prevalent recommended representative springerlink supplemental take text threshold trends undiagnosed version wave
Tagcloud (Difference) ?		adults cholesterol depth dyslipidemia english estimates excess german germany international interview lipoprotein lowering medication men persons prevalence prevalent recommended representative springerlink supplemental take text threshold trends undiagnosed version wave
Tagcloud (Intersection) ?