GCM1 and CAMK1

Number of citations of the paper that reports this interaction (PMID 21791615)
4

Data Source:
BioGRID (enzymatic study)

		GCM1	CAMK1
Gene Name		glial cells missing homolog 1 (Drosophila)	calcium/calmodulin-dependent protein kinase I
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Zinc Ion Binding	Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Fate Commitment Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Branching Involved In Labyrinthine Layer Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development	Protein Phosphorylation Nucleocytoplasmic Transport Cell Cycle Signal Transduction Positive Regulation Of Neuron Projection Development Regulation Of Protein Localization Regulation Of Protein Binding Positive Regulation Of Protein Export From Nucleus Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Dendritic Spine Development Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CAMK1 CREBBP DUSP23 HDAC1 HDAC3 HDAC4 HDAC5 SENP1 UBE2I	15 interactors: APP ATF1 CALM1 CAMKK1 CAMKK2 CCND1 CDK4 CDKN1B EIF4G3 GAPDH GCM1 HDAC5 MARK2 NOS1 SYN1
Entrez ID		8521	8536
HPRD ID		04757	05412
Ensembl ID		ENSG00000137270	ENSG00000134072
Uniprot IDs		Q9NP62	B0YIY3 Q14012
PDB IDs			4FG7 4FG8 4FG9 4FGB
Enriched GO Terms of Interacting Partners?		Histone H4 Deacetylation Histone H3 Deacetylation Histone H3-K9 Modification Histone Deacetylation Protein Deacetylation Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Notch Signaling Pathway Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Protein Metabolic Process Negative Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Myotube Differentiation Chromosome Organization Regulation Of Skeletal Muscle Fiber Development Regulation Of Protein Binding Regulation Of Muscle Cell Differentiation Negative Regulation Of Striated Muscle Cell Differentiation Chromatin Remodeling Osteoblast Development Protein Sumoylation Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Binding Regulation Of Cell Differentiation Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Osteoblast Differentiation Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Myotube Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Translation Signaling Cell Communication Regulation Of Phosphorus Metabolic Process Response To Metal Ion Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-cysteine S-nitrosylation Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Protein Metabolic Process Response To Organic Substance Phosphorylation Positive Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Organic Substance Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cell Cycle Phase Transition Regulation Of Phosphorylation Response To Inorganic Substance Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Response To Organic Cyclic Compound Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Response To Drug Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cell Cycle Response To Abiotic Stimulus Regulation Of Cell Cycle Arrest Signal Transduction Regulation Of Catalytic Activity Cellular Protein Modification Process Cellular Response To Stimulus Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Protein Metabolic Process Response To Stress Notch Signaling Pathway Protein Phosphorylation
Tagcloud ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Difference) ?		blastocysts bts cdh3 cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Intersection) ?