WBSCR16 and RBBP6

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		WBSCR16	RBBP6
Gene Name		Williams-Beuren syndrome chromosome region 16	retinoblastoma binding protein 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Mitochondrion	Nucleoplasm Chromosome Nucleolus Cytoplasm Microtubule Organizing Center
	Molecular Function	Poly(A) RNA Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Poly(A) RNA Binding
	Biological Process	Biological_process	In Utero Embryonic Development Multicellular Organism Growth Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Embryonic Organ Development Somite Development
Pathways
Drugs
Diseases
GWAS			Brain structure ( 20171287) Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: ATXN1 BRCA1 NME6 RBBP6	32 interactors: ACOT13 ANAPC16 APOH ASGR1 CAPZA2 CD81 ETS1 EVA1C FBXO7 GLUL GRB2 HP KHDRBS3 LINC00305 LRCH4 MAD2L2 NDUFB9 NEK6 PIAS1 PLG RBP4 RPS14 SMN1 SPP1 TPT1 UBE2I UPF3B VAV2 WBSCR16 YBX1 ZBTB38 ZFYVE9
Entrez ID		81554	5930
HPRD ID		15654	02964
Ensembl ID		ENSG00000174374	ENSG00000122257
Uniprot IDs		Q8IW88 Q8N572 Q96I51	Q7Z6E9
PDB IDs			2C7H 2YSA 2YUR 3ZTG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Histone H3-K9 Acetylation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Response To Radiation Negative Regulation Of Cell Cycle DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Cell Cycle Process Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Protein Ubiquitination Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Postreplication Repair Positive Regulation Of Protein Acetylation Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Gene Expression By Genetic Imprinting GTP Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors UTP Biosynthetic Process GTP Metabolic Process UTP Metabolic Process Genetic Imprinting CTP Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint	Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Cellular Component Assembly Negative Regulation Of Fibrinolysis Wound Healing Regulation Of Fibrinolysis Blood Coagulation Hemostasis Response To Wounding Response To External Stimulus Regulation Of Blood Coagulation Response To Stress Protein Sumoylation Regulation Of Wound Healing Mitotic Nuclear Division Regulation Of Body Fluid Levels Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Signaling Positive Regulation Of Blood Coagulation Regulation Of Immune System Process Immune System Process Reproductive Process Endocytosis Positive Regulation Of Coagulation Negative Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of SUMO Transferase Activity Protein Complex Assembly Positive Regulation Of Wound Healing Positive Regulation Of Metabolic Process Placenta Development Platelet Activation Cell Division Regulation Of Cell Proliferation Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Blood Coagulation Posttranscriptional Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Labyrinthine Layer Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Differentiation Regulation Of Lipid Kinase Activity Negative Regulation Of Coagulation Glutamine Biosynthetic Process
Tagcloud ?		7q11 acetylgalactosaminyltransferase beuren chaperone characterization deleted dnaj encode exchanging flanking haploinsufficiency homologies methyltransferase nol1 nop2 phenotypical rcc1 sun williams	associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs
Tagcloud (Difference) ?		7q11 acetylgalactosaminyltransferase beuren chaperone characterization deleted dnaj encode exchanging flanking haploinsufficiency homologies methyltransferase nol1 nop2 phenotypical rcc1 sun williams	associates au competes core distal dwnn fos implicate initially iso3 isoform jun machinery mrnas multisubunit name poly polyadenylation precursors processing retinoblastoma rich rnas transcript untranslated unusual usage utrs
Tagcloud (Intersection) ?