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CEP70 and MCM10
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CEP70
MCM10
Gene Name
centrosomal protein 70kDa
minichromosome maintenance complex component 10
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Nuclear Membrane
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
Protein Binding
DNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Cell Proliferation
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
G2/M Checkpoints
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
Regulation of DNA replication
M/G1 Transition
Activation of the pre-replicative complex
Cell Cycle, Mitotic
G1/S Transition
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Drugs
Diseases
GWAS
Protein-Protein Interactions
134 interactors:
ABT1
AKAP17A
ARHGEF3
ATP5O
ATXN7
BARD1
BEX2
BRMS1
BYSL
C11orf57
C1orf35
C7orf25
C8orf33
CARD9
CCDC85B
CCDC94
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
DAZAP2
DDX41
DDX6
DIEXF
DNAJB11
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM214B
FAM64A
GATAD2B
GCC1
GPATCH2L
GPATCH4
GPX7
HAUS1
HMGB4
HSPD1
IK
IQCE
KANK2
KANSL1
KAT7
KDM1A
KRT31
LAMTOR5
LENG1
LENG8
LIN37
MCM10
MEST
METTL17
MFAP1
MRPL44
NIPSNAP3A
NKAP
NOL12
NOP2
NRIP1
NUSAP1
PAM16
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PRKRIP1
PRPF31
PSMA1
RCOR3
RPL13
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TCEB3
TCEB3B
TEAD4
TRIM29
TRIM42
TSGA10IP
TSHZ3
TTC25
TTLL10
TXLNB
UTP11L
UTP14A
ZBTB16
ZBTB24
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZGPAT
ZNF136
ZNF148
ZNF169
ZNF227
ZNF239
ZNF266
ZNF302
ZNF329
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF439
ZNF490
ZNF555
ZNF572
ZNF578
ZNF587
ZSCAN12
32 interactors:
APP
CALCOCO2
CCDC85B
CCND1
CCND3
CDC45
CDC5L
CDC6
CDC7
CDK6
CDKN1A
CDKN2A
CEP70
CEP72
DPPA2
GOLGA2
HAUS1
HOOK2
IKBKG
KRT15
MCM2
MCM3
MCM6
MCM7
NINL
ORC2
ORC3
ORC4
TRIM37
VPRBP
ZBTB43
ZBTB8A
Entrez ID
80321
55388
HPRD ID
16779
11297
Ensembl ID
ENSG00000114107
ENSG00000065328
Uniprot IDs
B7Z2D2
Q8NHQ1
Q7L590
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Transcription, DNA-templated
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Metabolic Process
Cellular Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
RRNA Processing
Regulation Of Cellular Process
RRNA Metabolic Process
Ribosomal Small Subunit Biogenesis
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
MRNA Metabolic Process
Metabolic Process
Ribosome Biogenesis
Histone H3-K9 Dimethylation
RNA Processing
Chromatin Organization
Histone Modification
Maturation Of SSU-rRNA
Chromosome Organization
Cell Death
Death
Histone H3-K9 Trimethylation
Peptidyl-lysine Dimethylation
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Apoptotic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Mitotic Cell Cycle Process
Cell Cycle
Cell Cycle Process
DNA Replication Initiation
DNA-dependent DNA Replication
DNA Replication
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
DNA Metabolic Process
Regulation Of Cell Cycle Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
Macromolecule Biosynthetic Process
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
DNA Duplex Unwinding
DNA Geometric Change
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
DNA Unwinding Involved In DNA Replication
Cellular Nitrogen Compound Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Regulation Of Mitotic Cell Cycle
Cell Division
Biosynthetic Process
DNA Conformation Change
Double-strand Break Repair Via Break-induced Replication
Nitrogen Compound Metabolic Process
Organelle Organization
Chromosome Organization
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Cellular Response To DNA Damage Stimulus
Cell Cycle Checkpoint
G2/M Transition Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Phosphorylation
Tagcloud
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Difference)
?
cerevisiae
deadpan
delay
discs
driver
drosophila
enhancer
eye
eyes
gal4
gmr
imaginal
interference
involvement
klingon
knockdown
lacz
maintenance
mini
monitor
morphology
ommatidia
phases
photoreceptor
r7
replication
rough
surprisingly
Tagcloud (Intersection)
?