TBC1D17 and GABARAPL1

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TBC1D17	GABARAPL1
Gene Name		TBC1 domain family, member 17	GABA(A) receptor-associated protein like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Autophagic Vacuole Cytosol Cytoplasmic Vesicle	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	Rab GTPase Activator Activity Protein Binding	Protein Binding Microtubule Binding Tat Protein Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Autophagy Protein Transport Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Regulation Of Cilium Assembly	Autophagic Vacuole Assembly Mitochondrion Degradation Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ASCC2 CALCOCO1 CCT5 CDKN2D DHX29 FBL GABARAPL1 GPS1 GTF3C1 MAP1LC3A MAP1LC3B NIPSNAP1 OPTN RAB1A RAB5A RAB5B RAB5C SLC1A5 TAX1BP1	35 interactors: AHNAK2 ATG4A ATG4B ATG4D CALCOCO2 DVL2 FAM134C FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAPK15 OPRK1 RABGAP1 RABGAP1L SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 VDR
Entrez ID		79735	23710
HPRD ID		15471	07601
Ensembl ID		ENSG00000104946	ENSG00000139112
Uniprot IDs		Q9HA65	Q9H0R8
PDB IDs			2L8J 2R2Q
Enriched GO Terms of Interacting Partners?		Macroautophagy Autophagic Vacuole Assembly Cellular Response To Starvation Rab Protein Signal Transduction Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Nucleophagy Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Plasma Membrane To Endosome Transport Ras Protein Signal Transduction Response To External Stimulus Cellular Response To Nitrogen Starvation Cellular Response To Stress Membrane Fusion Cytoplasmic Transport Regulation Of Endocytosis Membrane Organization Organelle Assembly Response To Stimulus Endosomal Transport Intracellular Protein Transport Response To Stress Histone Glutamine Methylation Extracellular Amino Acid Transport Small GTPase Mediated Signal Transduction Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Peptidyl-glutamine Methylation Golgi Organization Response To Other Organism Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Response To Biotic Stimulus Regulation Of Vesicle-mediated Transport Interleukin-8 Production SnoRNA Metabolic Process Negative Regulation Of Receptor Recycling Cellular Protein Localization Mitochondrion Organization Protein Transport Negative Regulation Of Intracellular Signal Transduction Vesicle-mediated Transport Endomembrane System Organization 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Autophagy Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Signaling Protein Delipidation Mitochondrion Degradation Organelle Disassembly Regulation Of Metabolic Process Macroautophagy Cellular Response To Nitrogen Starvation Retrograde Transport, Endosome To Golgi Cellular Response To Nutrient Levels Nucleophagy Response To Starvation C-terminal Protein Lipidation Endosomal Transport Cellular Response To Extracellular Stimulus Protein Processing Response To Nutrient Levels Positive Regulation Of Autophagy Response To Extracellular Stimulus Autophagic Vacuole Assembly Cellular Response To Starvation Negative Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Mitochondrion Organization Negative Regulation Of Viral Process Vacuole Organization Regulation Of Autophagy Positive Regulation Of Viral Genome Replication Protein Lipidation Intracellular Transport Lipoprotein Biosynthetic Process Cellular Localization Response To Stress Establishment Of Localization In Cell Positive Regulation Of Protein Metabolic Process
Tagcloud ?			2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Difference) ?			2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Intersection) ?