BAG6 and CTCFL

Number of citations of the paper that reports this interaction (PMID 18765639)
22

Data Source:
BioGRID (two hybrid)

		BAG6	CTCFL
Gene Name		BCL2-associated athanogene 6	CCCTC-binding factor (zinc finger protein)-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Protein Binding Histone Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane	Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Cell Cycle Positive Regulation Of Gene Expression Histone Methylation DNA Methylation Involved In Gamete Generation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Histone H3-K4 Methylation
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 23894747)	Obesity-related traits ( 23251661) Response to statin therapy ( 20339536) Type 2 diabetes ( 23300278)
Protein-Protein Interactions		102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9	7 interactors: BAG6 BRCA1 HIST1H1A HIST1H3A HIST2H2AC PRMT7 ZDHHC17
Entrez ID		7917	140690
HPRD ID		00808	09512
Ensembl ID		ENSG00000204463	ENSG00000124092
Uniprot IDs		P46379	A6XGM0 A6XGM9 A6XGN2 A6XGN4 Q8NI51
PDB IDs		1WX9 4DWF 4EEW
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction	Regulation Of Gene Expression By Genetic Imprinting Regulation Of Gene Expression, Epigenetic Genetic Imprinting Chromatin Organization Chromosome Organization DNA Methylation DNA Modification Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Signal Transduction By P53 Class Mediator Nucleosome Assembly Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Positive Regulation Of Histone H3-K9 Acetylation Cellular Macromolecular Complex Assembly Gamete Generation Chromatin Assembly Organelle Organization Nucleosome Organization Chromatin Assembly Or Disassembly Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Protein-DNA Complex Assembly Sexual Reproduction Cellular Component Assembly Multicellular Organismal Reproductive Process DNA Packaging Intrinsic Apoptotic Signaling Pathway Multicellular Organism Reproduction Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Chromosome Segregation Dosage Compensation By Inactivation Of X Chromosome Tail-anchored Membrane Protein Insertion Into ER Membrane Protein K6-linked Ubiquitination Protein Insertion Into ER Membrane Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Reproduction DNA Metabolic Process Histone H4-R3 Methylation DNA Replication-dependent Nucleosome Assembly DNA Conformation Change Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Peptidyl-arginine N-methylation Regulation Of Histone H4 Acetylation
Tagcloud ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	boundaries causal compact demethylation depleted finger functionally generating h3k27me3 inactive incorporation inducer insulator insulators iptg lac laci mark modification neighbouring ones preceded removes requirement separate spreading thereby variant
Tagcloud (Difference) ?		biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a	boundaries causal compact demethylation depleted finger functionally generating h3k27me3 inactive incorporation inducer insulator insulators iptg lac laci mark modification neighbouring ones preceded removes requirement separate spreading thereby variant
Tagcloud (Intersection) ?