TUBA4A and STARD13

Number of citations of the paper that reports this interaction (PMID 14697242)
13

Data Source:
HPRD (two hybrid, in vivo)

		TUBA4A	STARD13
Gene Name		tubulin, alpha 4a	StAR-related lipid transfer (START) domain containing 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Microtubule Extracellular Vesicular Exosome	Lipid Particle Cytosol Mitochondrial Membrane
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	GTPase Activator Activity Protein Binding Lipid Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Platelet Degranulation Protein Folding Organelle Organization Microtubule-based Process Blood Coagulation Platelet Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Transport of connexons to the plasma membrane Hedgehog 'off' state Platelet degranulation Formation of tubulin folding intermediates by CCT/TriC Regulation of PLK1 Activity at G2/M Transition Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Gap junction trafficking and regulation Response to elevated platelet cytosolic Ca2+ Recruitment of mitotic centrosome proteins and complexes Gap junction assembly Gap junction trafficking Factors involved in megakaryocyte development and platelet production Resolution of Sister Chromatid Cohesion Platelet activation, signaling and aggregation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes M Phase Intraflagellar transport Post-chaperonin tubulin folding pathway Loss of Nlp from mitotic centrosomes MHC class II antigen presentation Protein folding Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Signaling by Hedgehog Chaperonin-mediated protein folding Centrosome maturation	Rho GTPase cycle Signaling by Rho GTPases
Drugs		Vincristine Podofilox Epothilone D Epothilone B Cabazitaxel
Diseases
GWAS			Body mass index (asthmatics) ( 23517042) Intracranial aneurysm ( 20364137)
Protein-Protein Interactions		49 interactors: APC ARHGAP1 B4GALT1 BCAR1 BRCA1 C4orf17 CALB2 EGFR ENO2 EPB41 FYN GNAI2 GPHN GRM7 HDAC6 HSPH1 LGALS2 LTA MAGED1 MAP1A MAP1LC3A MAPT MARK4 MYC NCALD PARK2 PFDN4 PLK1 RAB8B RAC1 RACGAP1 RBM23 RTN4 S100A8 SIAH1 SIMC1 SIRT2 STARD13 SYK TAOK2 TBCB TBCE TCP1 TM4SF1 UCHL5 VAV1 VDAC1 YWHAG ZAP70	12 interactors: BAI2 EPB41L1 HMGCR HSP90AA1 HSP90AB1 ITPR1 KIF1B SMAD1 SMARCD3 TAX1BP1 TUBA1A TUBA4A
Entrez ID		7277	90627
HPRD ID		01851	11607
Ensembl ID		ENSG00000127824	ENSG00000133121
Uniprot IDs		A8MUB1 P68366	B2R789 B3KRK6 Q9Y3M8
PDB IDs			2H80 2JW2 2PSO
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Response To Stress Programmed Cell Death Cell Death Death Positive Regulation Of Apoptotic Process Regulation Of Signaling Apoptotic Process Cell Migration Cell Communication Regulation Of Cellular Component Organization Positive Regulation Of Signal Transduction Response To Stimulus Regulation Of Signal Transduction Cell Motility Regulation Of Intracellular Signal Transduction Response To Growth Factor Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Stimulus Intracellular Signal Transduction Regulation Of Catalytic Activity Locomotion Movement Of Cell Or Subcellular Component Response To Organic Substance Signaling Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Organelle Organization 'de Novo' Posttranslational Protein Folding Cellular Response To Growth Factor Stimulus 'de Novo' Protein Folding Neurotrophin TRK Receptor Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Metabolic Process Neurotrophin Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Leukocyte Migration Signal Transduction Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Localization Regulation Of Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Organelle Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Regulation Of Microtubule-based Process Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Protein Metabolic Process	Cellular Response To Interleukin-4 Response To Interleukin-4 Protein Folding Cellular Protein Complex Assembly G2/M Transition Of Mitotic Cell Cycle Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Organic Substance Protein Complex Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Cellular Macromolecular Complex Assembly Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Mitotic Cell Cycle Phase Transition Phagocytosis Cell Cycle Phase Transition Regulation Of Muscle Cell Apoptotic Process Fc Receptor Signaling Pathway Defense Response Immune Response-activating Cell Surface Receptor Signaling Pathway 'de Novo' Posttranslational Protein Folding Regulation Of Nitric Oxide Biosynthetic Process 'de Novo' Protein Folding Vesicle-mediated Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Heat Innate Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Polymerization Immune Response-regulating Signaling Pathway Cellular Response To Organic Substance Response To Heat Cellular Component Assembly Response To Abiotic Stimulus Voluntary Musculoskeletal Movement Cardiac Right Ventricle Formation Protein Import Into Mitochondrial Outer Membrane Establishment Of Localization In Cell Response To Unfolded Protein Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Binding Cellular Response To Cytokine Stimulus Regulation Of Reactive Oxygen Species Metabolic Process
Tagcloud ?		34x10 abl1 applying await biology fyn gwas hypothesised illustrates inpp5d interactome interactomes interactor interactors kif1b loci pairwise phenotypes pik3r1 plcg1 prioritisation prioritization prkcd shared trait ubc unpredictable unravel	aberrant abilities addressed appearing bioinformatics certified clinicopathological colony colorectal corresponding crc curve distant healing indicator invasion kaplan luciferase lymphatic meier metastasis mimics mir nats poorer tnm untranslated utr wound
Tagcloud (Difference) ?		34x10 abl1 applying await biology fyn gwas hypothesised illustrates inpp5d interactome interactomes interactor interactors kif1b loci pairwise phenotypes pik3r1 plcg1 prioritisation prioritization prkcd shared trait ubc unpredictable unravel	aberrant abilities addressed appearing bioinformatics certified clinicopathological colony colorectal corresponding crc curve distant healing indicator invasion kaplan luciferase lymphatic meier metastasis mimics mir nats poorer tnm untranslated utr wound
Tagcloud (Intersection) ?