TPM3 and VPS52

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TPM3	VPS52
Gene Name		tropomyosin 3	vacuolar protein sorting 52 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Growth Cone Cortical Cytoskeleton Filamentous Actin Cleavage Furrow Extracellular Vesicular Exosome	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Actin Binding	Protein Binding Syntaxin Binding
	Biological Process	Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 FAM9C FBXO5 HDDC3 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2
Entrez ID		7170	6293
HPRD ID		01840	09142
Ensembl ID		ENSG00000143549	ENSG00000223501
Uniprot IDs		B4DQ80 P06753 Q5VU58 Q5VU63 Q8TCG3	B4DNI9 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?		Actomyosin Structure Organization Organelle Organization Actin Filament-based Process Regulation Of Organelle Organization Cellular Component Assembly Actin-myosin Filament Sliding Muscle Filament Sliding Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin-mediated Cell Contraction Regulation Of Cytoskeleton Organization Actin Filament Organization Actin Filament-based Movement Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Pointed-end Actin Filament Capping Regulation Of Chromosome Segregation Regulation Of Actin Polymerization Or Depolymerization Myofibril Assembly Regulation Of Actin Filament Length Cell-cell Junction Organization Regulation Of Mitotic Cell Cycle Muscle Contraction Cell Division Cell Cycle Muscle System Process Organelle Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Cell Development Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Regulation Of Muscle Contraction Positive Regulation Of Transcription Factor Import Into Nucleus Striated Muscle Cell Development Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Transforming Growth Factor Beta3 Production Inhibition Of APC-Cdc20 Complex Activity Regulation Of Metaphase Plate Congression Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Cytoskeleton Organization Regulation Of Mitotic Sister Chromatid Separation Arp2/3 Complex-mediated Actin Nucleation Muscle Cell Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Difference) ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler
Tagcloud (Intersection) ?