TP53BP2 and UBASH3A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TP53BP2	UBASH3A
Gene Name		tumor protein p53 binding protein 2	ubiquitin associated and SH3 domain containing A
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Cytosol Extracellular Vesicular Exosome
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Identical Protein Binding NF-kappaB Binding
	Biological Process	Cell Cycle Signal Transduction Central Nervous System Development Heart Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Signal Transduction Response To Ionizing Radiation Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Regulation Of Cytokine Production Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Celiac disease and Rheumatoid arthritis ( 21383967) Rheumatoid arthritis ( 20453842) Type 1 diabetes ( 19430480 18840781) Type 1 diabetes autoantibodies ( 21829393) Vitiligo ( 20410501)
Protein-Protein Interactions		58 interactors: APP ATPAF2 ATXN7 BAIAP2 BCL2 BCL2L1 CCDC92 CSNK2B CWF19L2 DCUN1D1 EEF1A1 GRB2 HIST1H2BC HNRNPUL1 KIF5A LMO4 MAGI1 MAPK8IP2 MRPL20 MTMR14 NAE1 NDC80 NUTM1 OTUB2 PLEKHN1 PLK1 POLR2L PPHLN1 PPP1CA PPP1CB PPP1CC PRKAB2 PRPF31 PTN RELA SIAH1 SIAH2 SSX2IP SUMO2 SUMO3 TANK TBC1D22B TCL1A TP53 TRAF4 TXLNA UBASH3A UNC119 USP4 UTP14A WWP1 WWP2 YAP1 YES1 YWHAG YWHAQ ZGPAT ZNF26	14 interactors: CBL CBS DAZAP2 KCNE1 KRT40 PARK2 REL SF3B4 SPRY2 TP53BP2 TRIM37 UBB UBC UBE2L3
Entrez ID		7159	53347
HPRD ID		11803	06904
Ensembl ID		ENSG00000143514	ENSG00000160185
Uniprot IDs		Q13625	P57075
PDB IDs		1YCS 2UWQ 4A63	2CRN
Enriched GO Terms of Interacting Partners?		Neuron Death Neuron Apoptotic Process Response To Radiation Regulation Of Signal Transduction Regulation Of Signaling Response To External Stimulus Negative Regulation Of Signal Transduction Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Signaling Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Apoptotic Signaling Pathway Cell Part Morphogenesis Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Phosphorylation Response To Light Stimulus Protein Modification By Small Protein Conjugation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Neuron Projection Morphogenesis Regulation Of Mitochondrion Organization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cell Projection Morphogenesis Axonogenesis Cellular Protein Modification Process Positive Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Regulation Of Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Protein Metabolic Process Response To Gamma Radiation Axon Development Regulation Of Extrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Generation Of Neurons Nervous System Development Cellular Response To Ionizing Radiation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Innate Immune Response Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Neuron Projection Development Neurogenesis Anatomical Structure Morphogenesis	Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Ubiquitination Positive Regulation Of Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Protein Ubiquitination I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Cell Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Organic Substance Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Cellular Response To Organic Substance Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Transferase Activity Viral Protein Processing Positive Regulation Of Protein Metabolic Process Aggresome Assembly Negative Regulation Of Cellular Response To Growth Factor Stimulus Signal Transduction By P53 Class Mediator Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Cycle Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Ubiquitin-dependent Protein Catabolic Process Glycogen Biosynthetic Process Intracellular Transport Of Virus
Tagcloud ?		adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Difference) ?		adenovirus angiotensin apoptosis array at2r bag3 bmp6 bmp7 bnipi cytokine downregulation du145 gadd45a hrk il6 il8 mapk microrna next numerous p44 pc r2 silence sirnas tnfsf10 trail transduced utilized
Tagcloud (Intersection) ?