THRB and NRBF2

Number of citations of the paper that reports this interaction (PMID 10786636)
2

Data Source:
HPRD (two hybrid)

		THRB	NRBF2
Gene Name		thyroid hormone receptor, beta	nuclear receptor binding factor 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Corepressor Activity Thyroid Hormone Receptor Activity Protein Binding Zinc Ion Binding Enzyme Binding Chromatin DNA Binding Sequence-specific DNA Binding Thyroid Hormone Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Sensory Perception Of Sound Negative Regulation Of Female Receptivity Regulation Of Heart Contraction Female Courtship Behavior Organ Morphogenesis Gene Expression Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Type I Pneumocyte Differentiation	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs		Liothyronine Levothyroxine Dextrothyroxine Liotrix [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid 3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione [4-(4-Hydroxy-3-Iodo-Phenoxy)-3,5-Diiodo-Phenyl]-Acetic Acid GC-24 {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid 1-(4-HEXYLPHENYL)PROP-2-EN-1-ONE
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) Red blood cell traits ( 23222517)	Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		58 interactors: ACVR1 ADAT3 ANP32A ATF2 BRD8 BTG1 C1D CAMK2B CCND1 CNOT1 COPS2 CTCF EIF3I ESR1 FOXO1 HDAC2 HDAC3 HMGN3 JMJD1C LRIF1 MECR MED1 MED21 MMS19 MPG NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NR2F6 NRBF2 NRIP1 NSD1 PPARGC1A PPARGC1B PRKDC PRMT1 PRMT2 PSMC3IP PSMC5 RANBP9 RARA ROBO4 RXRA RXRB RXRG SRC TBL1X TP53 TRIP10 TRIP12 TRIP13 TRIP4 TRIP6 TSG101 ZNHIT3	7 interactors: C1orf216 HNF4A IKBKG PPARA RARA RXRA THRB
Entrez ID		7068	29982
HPRD ID		07521	11401
Ensembl ID		ENSG00000151090	ENSG00000148572
Uniprot IDs		F1D8N7 P10828	B4DWS0 Q96F24
PDB IDs		1BSX 1N46 1NAX 1NQ0 1NQ1 1NQ2 1NUO 1Q4X 1R6G 1XZX 1Y0X 2J4A 2NLL 2PIN 3D57 3GWS 3IMY 3JZC
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Intracellular Receptor Signaling Pathway RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Chromatin Organization Chromosome Organization Transcription Initiation From RNA Polymerase II Promoter Response To Hormone Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Metabolic Process Chromatin Modification Intracellular Estrogen Receptor Signaling Pathway Cellular Response To Hormone Stimulus Signal Transduction Regulation Of Cellular Process Cellular Response To Stimulus Response To Steroid Hormone	Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Positive Regulation Of Transcription, DNA-templated Cellular Response To Hormone Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Lipid Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Ventricular Cardiac Muscle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Lipid Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Organ Morphogenesis Regulation Of RNA Metabolic Process Glandular Epithelial Cell Differentiation Nucleobase-containing Compound Metabolic Process Epithelium Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Negative Regulation Of RNA Biosynthetic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Response To Organic Substance Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process
Tagcloud ?		approximate bank carrying circular clarke clockwise ecori enabled endonuclease hybird kilobase kilobases lacz lambda limitation maxicell pbr322 phage pho phom phou plac plasmid plasmids plc17 regulon subcloned threefold transcribed	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Difference) ?		approximate bank carrying circular clarke clockwise ecori enabled endonuclease hybird kilobase kilobases lacz lambda limitation maxicell pbr322 phage pho phom phou plac plasmid plasmids plc17 regulon subcloned threefold transcribed	adam19 adamts16 adamts9 aggf1 altitude altitudes ccbe1 creld1 dahe dhp dwells f2rl1 fgf10 fgf5 foxm gdap1 gna14 involvements jmjd1c parp8 pla2g4a rhog rtel1 sweeps vegfc vps13a wuzhishan wzsp zfpm2
Tagcloud (Intersection) ?