PJA1 and MAGED1

Number of citations of the paper that reports this interaction (PMID 11959851)
20

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PJA1	MAGED1
Gene Name		praja ring finger 1, E3 ubiquitin protein ligase	melanoma antigen family D, 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Chromatin Nucleus Cytoplasm Plasma Membrane Protein Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Transcription Coactivator Activity Protein Binding
	Biological Process	Protein Ubiquitination Protein Catabolic Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK Programmed Cell Death p75 NTR receptor-mediated signalling Role of DCC in regulating apoptosis Extrinsic Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ASCC2 ATP5C1 ATXN3 ATXN3L EED ESPL1 EZH2 GSR HNRNPL JOSD1 KIF22 MAGED1 MDM2 NDN NDNL2 OTUB1 OTUB2 RIBC2 SPTBN1 STAM STAMBP SUZ12 UBC UBE2D2 UBE2D3 UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP7 USP8 ZNF440	49 interactors: AKAP9 BAG3 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 HIVEP1 KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 ROR2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488
Entrez ID		64219	9500
HPRD ID		02335	02202
Ensembl ID		ENSG00000181191	ENSG00000179222
Uniprot IDs		Q8NG27	Q9Y5V3
PDB IDs		2L0B
Enriched GO Terms of Interacting Partners?		Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Catabolic Process Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process DNA Repair Cellular Response To Stress Protein K63-linked Deubiquitination Regulation Of Protein Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Regulation Of Proteolysis Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Histone Modification Cell Cycle Process Metabolic Process Nitrogen Compound Metabolic Process Protein Polyubiquitination Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Chromosome Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Ubiquitination Cell Cycle Cytokinesis Protein Modification By Small Protein Conjugation Chromatin Modification Cellular Response To Oxygen Levels Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway	Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Binding Transcription, DNA-templated Metabolic Process Signal Transduction Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Cellular Response To Stimulus Positive Regulation Of Signal Transduction RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Signaling Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Embryo Development Radial Glia Guided Migration Of Purkinje Cell Cellular Process Macromolecule Biosynthetic Process Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Communication Positive Regulation Of Metabolic Process System Development Apoptotic Process Response To Stimulus
Tagcloud ?			allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Difference) ?			allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Intersection) ?