TINAGL1 and MED31

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TINAGL1	MED31
Gene Name		tubulointerstitial nephritis antigen-like 1	mediator complex subunit 31
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Extracellular Matrix Extracellular Vesicular Exosome	Nucleoplasm Mediator Complex
	Molecular Function	Scavenger Receptor Activity Extracellular Matrix Structural Constituent Cysteine-type Peptidase Activity Polysaccharide Binding Laminin Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding
	Biological Process	Proteolysis Receptor-mediated Endocytosis Immune Response Endosomal Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CAPN1 EP300 KRTAP10-3 KRTAP12-2 KRTAP4-2 LMO4 MDFI MED31 NOTCH2NL RBPMS SHBG SMAD9 TRIP13 UTP14A	58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1
Entrez ID		64129	51003
HPRD ID		07122	14382
Ensembl ID		ENSG00000142910	ENSG00000108590
Uniprot IDs		E7EUP2 Q9GZM7	Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Developmental Process Involved In Reproduction Transcription, DNA-templated RNA Biosynthetic Process Histone H2B Acetylation Primary Spermatocyte Growth Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process N-terminal Peptidyl-lysine Acetylation Nucleobase-containing Compound Metabolic Process Single Organism Reproductive Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Notch Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Reproductive Process Regulation Of Tubulin Deacetylation Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Protein Import Into Nucleus Macromolecule Biosynthetic Process Mullerian Duct Regression Tube Development Regulation Of Protein Localization To Nucleus Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleocytoplasmic Transport Nitrogen Compound Metabolic Process Positive Regulation By Host Of Viral Transcription Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching N-terminal Protein Amino Acid Acetylation Regulation Of Binding Regulation Of Intracellular Protein Transport Receptor Catabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Positive Regulation Of SMAD Protein Import Into Nucleus Female Meiosis I Spinal Cord Association Neuron Differentiation Response To Hypoxia Regulation Of SMAD Protein Import Into Nucleus Trophoblast Giant Cell Differentiation Anatomical Structure Regression Regulation Of Cell Fate Specification	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process
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