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SH2D4A and HMBOX1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SH2D4A
HMBOX1
Gene Name
SH2 domain containing 4A
homeobox containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
Phosphatase Binding
DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Phosphatase Activity
Transcription, DNA-templated
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
43 interactors:
ALAS1
CASK
CCDC172
CDR2
CEP70
CEP76
DBNL
FSD2
GOLGA2
GRB2
HCLS1
HMBOX1
IKZF1
KRT40
LDOC1
LZTS2
MAGEA11
MAGEA6
MTUS2
NECAB2
NINL
NUTM1
PDE4DIP
PNMA1
PPP1CB
PSTPIP1
RINT1
SH3GL1
SKAP1
SORBS2
SORBS3
SPAG5
STAM2
STX11
TACC1
TFIP11
TRAF2
TRIM23
TRIM27
UBXN11
USHBP1
VPS52
ZBTB16
48 interactors:
AEBP2
APP
ASB7
ATP5O
BYSL
C20orf195
C8orf33
CARD9
CBX8
CCNG1
DAB1
DYNLL2
ENTPD2
FAM13C
FAM161A
FAM206A
FAM74A4
FARS2
FRMD6
FXR2
KAT5
LNX1
MAGEH1
MFAP1
MORF4L1
MRPL11
MRPL28
PIP4K2B
PKD1P1
PRKAA1
PRKAA2
RBMY2FP
REEP6
RPL9
SAP30L
SFR1
SH2D4A
SNRPB2
TCEANC
UBA6
UBE2Z
VPS72
ZBTB24
ZMAT2
ZNF337
ZNF417
ZNF581
ZNF587
Entrez ID
63898
79618
HPRD ID
08340
07964
Ensembl ID
ENSG00000104611
ENSG00000147421
Uniprot IDs
Q9H788
D3DSU2
Q6NT76
PDB IDs
2CUF
4J19
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Positive Regulation Of NK T Cell Differentiation
G2/M Transition Of Mitotic Cell Cycle
Organelle Organization
Regulation Of Cytoskeleton Organization
Positive Regulation Of Granulocyte Differentiation
Mitotic Cell Cycle
Immune System Process
Positive Regulation Of Cytoskeleton Organization
Regulation Of Cell Adhesion
Positive Regulation Of T Cell Activation
Positive Regulation Of Homotypic Cell-cell Adhesion
Cell Division
Mitotic Cell Cycle Process
Positive Regulation Of Cell-cell Adhesion
Protein Complex Assembly
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Calcium Ion Import
Actin Filament Organization
Regulation Of T Cell Activation
Cytoskeleton Organization
Positive Regulation Of Cell Activation
Protein K63-linked Ubiquitination
Protein Trimerization
Cellular Protein Complex Assembly
Positive Regulation Of Immune System Process
Regulation Of Organelle Organization
Regulation Of Microtubule-based Process
Positive Regulation Of Neutrophil Differentiation
Spliceosomal Complex Disassembly
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Regulation Of Actin Cytoskeleton Organization
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Positive Regulation Of Alpha-beta T Cell Differentiation
Regulation Of Immune System Process
Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Actin Filament Polymerization
Positive Regulation Of Cellular Metabolic Process
Regulation Of Lymphocyte Activation
Negative Regulation Of ERBB Signaling Pathway
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Positive Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Cellular Localization
Cell Cycle Process
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Transcription, DNA-templated
Nitrogen Compound Metabolic Process
Chromatin Organization
Biosynthetic Process
Chromatin Modification
Cellular Metabolic Process
Regulation Of Energy Homeostasis
Positive Regulation Of Glycolytic Process
Chromosome Organization
Fatty Acid Homeostasis
Histone Modification
Histone-serine Phosphorylation
Cellular Response To Glucose Starvation
Regulation Of Glycolytic Process
Cholesterol Metabolic Process
Organelle Organization
Sterol Metabolic Process
Negative Regulation Of TOR Signaling
Cholesterol Biosynthetic Process
Translational Termination
Positive Regulation Of Autophagy
Neuron Recognition
Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration
Synaptic Target Recognition
Negative Regulation Of Glucosylceramide Biosynthetic Process
Cold Acclimation
Double-strand Break Repair
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Histone Phosphorylation
Sterol Biosynthetic Process
Protein Ubiquitination
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Anion Homeostasis
Translational Elongation
Protein Modification By Small Protein Conjugation
Regulation Of Gene Expression
Cellular Process
Regulation Of RNA Metabolic Process
Cerebellum Structural Organization
Tagcloud
?
adherens
aqp2
aqp3
bioinformatic
collecting
crebbp
ctnnb1
duct
elf3
enacbeta
enacgamma
esbl
flanking
gatad2b
gov
helixweb
http
hypotheses
isotope
junb
junctions
mnpd
mpkccd
nih
pser552
rangap1
scnn1b
scnn1g
vasopressin
Tagcloud (Difference)
?
adherens
aqp2
aqp3
bioinformatic
collecting
crebbp
ctnnb1
duct
elf3
enacbeta
enacgamma
esbl
flanking
gatad2b
gov
helixweb
http
hypotheses
isotope
junb
junctions
mnpd
mpkccd
nih
pser552
rangap1
scnn1b
scnn1g
vasopressin
Tagcloud (Intersection)
?