RXRG and DCK

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RXRG	DCK
Gene Name		retinoid X receptor, gamma	deoxycytidine kinase
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus Cytosol
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Steroid Hormone Receptor Activity 9-cis Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding	Deoxycytidine Kinase Activity ATP Binding Drug Binding Nucleoside Kinase Activity Protein Homodimerization Activity
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Peripheral Nervous System Development Heart Development Skeletal Muscle Tissue Development Gene Expression Neuron Differentiation Regulation Of Myelination Response To Retinoic Acid Steroid Hormone Mediated Signaling Pathway Retinoic Acid Receptor Signaling Pathway Protein Homotetramerization Transmembrane Transport Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus	Purine Nucleobase Metabolic Process Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleotide Metabolic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Phosphorylation Pyrimidine Nucleoside Salvage Purine-containing Compound Salvage Small Molecule Metabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters	Pyrimidine salvage reactions Purine metabolism Pyrimidine metabolism Metabolism of nucleotides Purine salvage
Drugs		Adapalene Bexarotene Acitretin Alitretinoin Tretinoin Etretinate
Diseases
GWAS		AIDS ( 19754311) Menarche (age at onset) ( 21102462) Personality dimensions ( 21368711)
Protein-Protein Interactions		29 interactors: CAMK2B CEBPZ CHGB CREBBP DCK HOXD4 ITGB3BP LRSAM1 MAP4 MPPED2 NCOA6 NCOR2 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR4A1 PNO1 PPARA PPARD PPARG RARA RARB RARG SRF THRA THRB VDR	5 interactors: DDX19B GOLM1 MED19 RXRG TFEC
Entrez ID		6258	1633
HPRD ID		01579	00507
Ensembl ID		ENSG00000143171	ENSG00000156136
Uniprot IDs		F1D8Q7 F1T097 P48443	F5CTF3 P27707
PDB IDs		2GL8	1P5Z 1P60 1P61 1P62 2A2Z 2A30 2A7Q 2NO0 2NO1 2NO6 2NO7 2NO9 2NOA 2QRN 2QRO 2ZI3 2ZI4 2ZI5 2ZI6 2ZI7 2ZI9 2ZIA 3HP1 3IPX 3IPY 3KFX 3MJR 3QEJ 3QEN 3QEO 4JLK 4L5B
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Intracellular Receptor Signaling Pathway Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Hormone Transcription, DNA-templated RNA Biosynthetic Process Cellular Response To Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Response To Lipid Positive Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Organic Substance Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Organic Substance Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Cholesterol Storage Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process
Tagcloud ?		band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr	affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying
Tagcloud (Difference) ?		band bands chromosome chromosomes cosmid cosmids cytogenetic encoded establishing heterodimeric location loci pairwise partners proximity q22 q23 q34 reference respond retinoic retinoid rxra rxrb rxrs separate tr vdr	affects agent approved bcl2l10 cda common continued cr decitabine determine furthermore hent1 indicate induce level marrow mds measured mechanisms metabolic metabolism mrna regulated relapse resistance response secondary therapeutic underlying
Tagcloud (Intersection) ?