RPLP1 and C15orf39

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RPLP1	C15orf39
Gene Name		ribosomal protein, large, P1	chromosome 15 open reading frame 39
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		34 interactors: ANKRD13B ASCC2 ATP5J2 BRD7 C11orf58 C15orf39 CDIPT CDK2AP2 CLIC1 CSNK2A1 EEF1A1 GEMIN7 GSK3B LRIF1 MAP1LC3B MPC2 NSF NUDT21 NUDT3 PDCD4 PFDN1 PPP2CB PTN RCHY1 RPA2 RPLP2 RPS6KA6 SAT1 SGOL1 TAB1 TPT1 TUBB2A UBE2D3 XRCC6	3 interactors: APP CTBP2 RPLP1
Entrez ID		6176	56905
HPRD ID		01611	13154
Ensembl ID		ENSG00000137818	ENSG00000167173
Uniprot IDs		P05386	Q6ZRI6
PDB IDs		2LBF 3J3B 4BEH
Enriched GO Terms of Interacting Partners?		Cellular Metabolic Process Negative Regulation Of Intracellular Signal Transduction Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Stress Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Response To Heat Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Growth Factor Negative Regulation Of MAPK Cascade Cellular Process Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Catabolic Process Nitrogen Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cell Cycle 'de Novo' Posttranslational Protein Folding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Spermidine Acetylation Superior Temporal Gyrus Development Golgi Vesicle Docking Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle 'de Novo' Protein Folding TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Cycle Phase Transition Cellular Response To Heat Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Viral Life Cycle Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Binding Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Chromatin Binding Axon Choice Point Recognition Neuron Remodeling MRNA Metabolic Process Viral Process White Fat Cell Differentiation Cellular Copper Ion Homeostasis RNA Metabolic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Viral Genome Replication Gene Expression Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Retinoic Acid Receptor Signaling Pathway Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Nucleobase-containing Compound Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Platelet Degranulation Positive Regulation Of Transcription, DNA-templated
Tagcloud ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded
Tagcloud (Difference) ?		altogether atrophy disrupted dysregulation eminence exerted fine folding ganglionic germline heterozygosity infertility lethality midbrain neocortex newborn p21cip1 p27kip1 perinatal pivotal pmefs premature reductions subsets tuning unfolded
Tagcloud (Intersection) ?