BCL6 and BLZF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BCL6	BLZF1
Gene Name		B-cell CLL/lymphoma 6	basic leucine zipper nuclear factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Replication Fork	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Lumen
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Enzyme Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Import Into Nucleus, Translocation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Morphogenesis Negative Regulation Of Cell-matrix Adhesion Germinal Center Formation Regulation Of Germinal Center Formation Negative Regulation Of B Cell Apoptotic Process Transcription, DNA-templated Inflammatory Response Cellular Response To DNA Damage Stimulus Rho Protein Signal Transduction Spermatogenesis Negative Regulation Of Cell Proliferation Actin Cytoskeleton Organization B Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of B Cell Proliferation Positive Regulation Of Histone Deacetylation Regulation Of Rho GTPase Activity Negative Regulation Of Mast Cell Cytokine Production Negative Regulation Of Rho Protein Signal Transduction Type 2 Immune Response Positive Regulation Of Apoptotic Process Regulation Of Memory T Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of Neuron Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Isotype Switching To IgE Isotypes Erythrocyte Development Regulation Of Inflammatory Response Regulation Of Immune Response Positive Regulation Of Cellular Component Movement Negative Regulation Of Cellular Senescence	Mitotic Cell Cycle Regulation Of Cell Growth Regulation Of Transcription From RNA Polymerase II Promoter Golgi Organization Cell Proliferation Golgi To Plasma Membrane Protein Transport
Pathways			Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		B cell non-Hodgkin lymphoma ( 23749188) PR interval ( 23534349) Pulmonary function (interaction) ( 23284291) Renal function-related traits (BUN) ( 22797727)
Protein-Protein Interactions		44 interactors: AES BCL11A BCL6B BCOR BLZF1 CDK19 CDK8 CHD3 CREBBP CUTC EP300 FBXO11 HDAC4 HDAC5 HDAC7 HDAC9 IRF4 JUN JUNB JUND KIFC3 LIMS3 MAPK1 MED17 MED6 MTA3 NCOR1 NCOR2 PELI1 PIN1 PML PPARD PRKD3 RAF1 RUNX1T1 SIAH1 SIN3A SP1 SPI1 TRAF1 WNK4 ZBTB16 ZBTB7A ZBTB7B	45 interactors: AKAP9 AMOTL2 BCL6 BEX2 CARD9 CCDC33 CHCHD3 CINP EWSR1 FBF1 FHL2 FRMD6 GEM GORASP2 HCLS1 HOXA1 IQUB KDM1A KLHL38 LMO1 LMO2 OAZ3 PRKAB2 PRMT6 PSMA1 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SMAD3 SRA1 SSX2 SUV39H2 TBC1D7 TRAPPC2L TSC22D4 TXNDC5 VPS28 ZBTB24 ZGPAT ZMAT1 ZNF410 ZZZ3
Entrez ID		604	8548
HPRD ID		00180	16367
Ensembl ID		ENSG00000113916	ENSG00000117475
Uniprot IDs		B5B0A5 P41182	Q9H2G9
PDB IDs		1R28 1R29 1R2B 2EN2 2EOS 2LCE 2YRM 3BIM 3E4U 3LBZ
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Hemopoiesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Immune System Development Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Notch Signaling Pathway Immune System Process DNA-templated Transcription, Initiation Response To Organic Substance Leukocyte Differentiation Chromatin Modification Cellular Protein Modification Process Developmental Process Nitrogen Compound Metabolic Process Organ Development Chromosome Organization	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Ras Protein Signal Transduction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Cell Cycle Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Organelle Organization Rab Protein Signal Transduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Cellular Amino Acid Metabolic Process Small GTPase Mediated Signal Transduction Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Intracellular Transport Positive Regulation Of Cellular Metabolic Process Immune System Development Negative Regulation Of Cell Death Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Response To Stimulus Establishment Of Localization In Cell Regulation Of Erythrocyte Differentiation
Tagcloud ?		ablated conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3 sin3a sin3b tafii32 tafii70 tafs terminalrepression tfiib zip
Tagcloud (Difference) ?		ablated conducive cor corepressors deacteylases erbaalpha erbbeta interactiondomains laz3 locks mad mxi physicalassociation rev rid rids rip13a rip13delta1 rpd3 rvr sin3 sin3a sin3b tafii32 tafii70 tafs terminalrepression tfiib zip
Tagcloud (Intersection) ?