RFX1 and NFIX

Number of citations of the paper that reports this interaction (PMID 12624117)
3

Data Source:
HPRD (in vitro, in vivo)

		RFX1	NFIX
Gene Name		regulatory factor X, 1 (influences HLA class II expression)	nuclear factor I/X (CCAAT-binding transcription factor)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Transcription From RNA Polymerase II Promoter Cerebellar Purkinje Cell Layer Development Cerebellar Granule Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Differentiation
Pathways			RNA Polymerase III Transcription RNA Polymerase III Transcription Termination RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3	7 interactors: JMJD6 NFIB PIR QRICH1 RFX1 SKI ZNF614
Entrez ID		5989	4784
HPRD ID		02476	01234
Ensembl ID		ENSG00000132005	ENSG00000008441
Uniprot IDs		P22670	B4DHW2 D2DXM9 Q14938
PDB IDs		1DP7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Hindbrain Development Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development BMP Signaling Pathway Regulation Of Binding System Development SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Multicellular Organismal Development Mesonephros Development Biosynthetic Process Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transforming Growth Factor Beta Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Respiratory System Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA Binding Lung Ciliated Cell Differentiation Histone H3-R2 Demethylation Histone H4-R3 Demethylation Negative Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Principal Sensory Nucleus Of Trigeminal Nerve Development Negative Regulation Of Mesenchymal Cell Proliferation Involved In Lung Development Tube Development Nose Morphogenesis Nitrogen Compound Metabolic Process Retina Development In Camera-type Eye Glial Cell Differentiation Negative Regulation Of Histone Deacetylation Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Mesenchymal Cell Proliferation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Gliogenesis Recognition Of Apoptotic Cell Type II Pneumocyte Differentiation Clara Cell Differentiation Myeloid Cell Differentiation Lung Development Respiratory Tube Development Regulation Of Binding Anterior Commissure Morphogenesis Negative Regulation Of Activin Receptor Signaling Pathway Telencephalon Development Negative Regulation Of Glial Cell Proliferation Leukocyte Differentiation Lung Secretory Cell Differentiation
Tagcloud ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary
Tagcloud (Difference) ?		243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol	aluy anomalies cleared craniofacial decay difficulties dimerization dysfunctional encode exon frameshift grossly homogeneous intron ligation malformation marshall mendelian mss multiplex nonsense osseous portion preserved recurrent smith splice thrive vary
Tagcloud (Intersection) ?