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RBL1 and BEGAIN
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
HPRD
(two hybrid)
RBL1
BEGAIN
Gene Name
retinoblastoma-like 1
brain-enriched guanylate kinase-associated
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Membrane
Dendrite
Neuronal Cell Body
Molecular Function
Protein Binding
Transcription Factor Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Mitotic Cell Cycle
Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Expression
Viral Process
Chromatin Modification
Regulation Of Lipid Kinase Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Cell Cycle
Pathways
Loss of Function of TGFBR2 in Cancer
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 LBD Mutants in Cancer
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Generic Transcription Pathway
Mitotic G1-G1/S phases
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
G1 Phase
Loss of Function of SMAD4 in Cancer
TGFBR1 KD Mutants in Cancer
G0 and Early G1
Loss of Function of TGFBR1 in Cancer
Cell Cycle, Mitotic
Cyclin D associated events in G1
Signaling by TGF-beta Receptor Complex in Cancer
Signaling by TGF-beta Receptor Complex
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Menarche (age at onset) (
21102462
)
Protein-Protein Interactions
51 interactors:
AOX1
BEGAIN
BRCA1
BRF1
CCNA1
CCNA2
CCND1
CCNE1
CDK2
CDK4
CDK6
CEBPA
CREG1
DGKZ
DHX30
DYRK1A
E2F4
E2F5
EPHA2
FN1
GOLGA2
HDAC1
ID2
IRF3
KDM5A
LAMB2
MAPK6
MCM7
MYBL2
MYC
NR2E3
NR4A1
NUCB1
PHB
PLSCR1
PPP2R3A
RBBP8
RBBP9
RINT1
SMAD2
SMAD3
SMAD4
SMARCA4
SNRPD3
SNW1
SP1
SUV39H1
SUV420H2
TAF1
TOP1
USP4
23 interactors:
ABLIM1
APP
BAHD1
CATSPER1
DEF6
DLG1
DLG4
DTNB
ENKD1
FAM107A
GFI1B
HGS
HID1
KIAA0408
QSOX1
RBL1
RIBC2
TRIM27
USP2
ZFP64
ZNF250
ZNF417
ZNF774
Entrez ID
5933
57596
HPRD ID
00312
06459
Ensembl ID
ENSG00000080839
ENSG00000183092
Uniprot IDs
P28749
Q9BUH8
PDB IDs
1H28
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Cell Cycle
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-templated Transcription, Initiation
Positive Regulation Of Cellular Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Regulation Of Gene Expression
Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Mitotic Cell Cycle
Macromolecule Biosynthetic Process
RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
Regulation Of RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Cell Cycle
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Gene Expression
Nitrogen Compound Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cell Proliferation
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Biosynthetic Process
Cell Cycle Process
Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Biosynthetic Process
Mitotic Cell Cycle Process
Negative Regulation Of Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Multicellular Organismal Development
Receptor Localization To Synapse
Regulation Of Metabolic Process
Protein Localization To Synapse
Regulation Of Gene Expression
Cell Recognition
Regulation Of Transcription, DNA-templated
Regulation Of Cellular Process
Cortical Actin Cytoskeleton Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Establishment Or Maintenance Of Apical/basal Cell Polarity
Axon Guidance
Cortical Cytoskeleton Organization
Regulation Of RNA Metabolic Process
Transcription, DNA-templated
Regulation Of Ion Transmembrane Transport
Nucleobase-containing Compound Metabolic Process
RNA Biosynthetic Process
Heterocycle Metabolic Process
RNA Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Receptor Clustering
Axonogenesis
Response To Brefeldin A
Locomotory Behavior
Gene Expression
Negative Regulation Of Cellular Metabolic Process
Nucleotide Phosphorylation
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Cell-cell Recognition
Chemotaxis
Regulation Of Membrane Potential
Regulation Of Ion Transport
Negative Regulation Of Transcription, DNA-templated
Neuron Projection Morphogenesis
Negative Regulation Of Interleukin-2 Secretion
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Nucleic Acid-templated Transcription
Nitrogen Compound Metabolic Process
Neuromuscular Process Controlling Balance
Synapse Assembly
Negative Regulation Of RNA Biosynthetic Process
Regulation Of ERBB Signaling Pathway
Collateral Sprouting In Absence Of Injury
Cell Morphogenesis Involved In Differentiation
Tagcloud
?
accounts
adenocarcinoma
applicable
assist
deaths
diagnostics
e2f6
effort
expended
facilitate
gold
hmga1
hnrpd
interactome
irf1
lung
mirna
nsclc
qpcr
screen
silico
sub
suitable
suv39h1
tf
tfdp1
transcriptomics
vital
worldwide
Tagcloud (Difference)
?
accounts
adenocarcinoma
applicable
assist
deaths
diagnostics
e2f6
effort
expended
facilitate
gold
hmga1
hnrpd
interactome
irf1
lung
mirna
nsclc
qpcr
screen
silico
sub
suitable
suv39h1
tf
tfdp1
transcriptomics
vital
worldwide
Tagcloud (Intersection)
?