RAN and XPO7

Number of citations of the paper that reports this interaction (PMID 11024021)
15

Data Source:
BioGRID (affinity chromatography technology, pull down)

		RAN	XPO7
Gene Name		RAN, member RAS oncogene family	exportin 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Melanosome Recycling Endosome Extracellular Vesicular Exosome	Nucleus Nuclear Pore Cytoplasm
	Molecular Function	Chromatin Binding Transcription Coactivator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Poly(A) RNA Binding Androgen Receptor Binding	Nuclear Export Signal Receptor Activity Ran GTPase Binding
	Biological Process	Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus DNA Metabolic Process Protein Import Into Nucleus Protein Export From Nucleus Mitotic Spindle Organization Mitotic Nuclear Division Signal Transduction Small GTPase Mediated Signal Transduction Spermatid Development Gene Expression Viral Process Viral Life Cycle Actin Cytoskeleton Organization Androgen Receptor Signaling Pathway Positive Regulation Of Protein Binding Cellular Protein Complex Localization Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Cell Division Intracellular Transport Of Virus	Protein Export From Nucleus MRNA Transport
Pathways		Transcriptional regulation by small RNAs Metabolism of lipids and lipoproteins Nuclear import of Rev protein HIV Infection Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Host Interactions of HIV factors MicroRNA (miRNA) biogenesis Influenza Infection Interactions of Rev with host cellular proteins Late Phase of HIV Life Cycle Influenza Life Cycle Regulation of cholesterol biosynthesis by SREBP (SREBF) Export of Viral Ribonucleoproteins from Nucleus HIV Life Cycle Rev-mediated nuclear export of HIV RNA NEP/NS2 Interacts with the Cellular Export Machinery
Drugs
Diseases
GWAS			Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		55 interactors: ABL1 ADRB2 AR ASAP2 BCAR1 BMPR1B CSE1L EP300 GADD45G GIT1 IPO11 IPO13 IPO5 IPO7 KIAA1377 KPNA2 KPNB1 MBP MSL1 NEK9 NR3C1 NSMF NUP153 NUP50 NUPR1 NUTF2 NXF1 NXT1 PAK4 PTMA RANBP1 RANBP10 RANBP2 RANBP3 RANBP9 RANGAP1 RANGRF RCC1 RGPD5 RPL7 SMAD1 SMAD2 SMARCB1 SMURF2 SNUPN SPAG8 SSRP1 TGFBR1 TNPO1 TNPO2 XPO1 XPO4 XPO5 XPO7 XPOT	8 interactors: DDX19B MAPK9 NUP153 PDPK1 RAN TAB1 USO1 XPOT
Entrez ID		5901	23039
HPRD ID		03109	05846
Ensembl ID			ENSG00000130227
Uniprot IDs		B4DV51 P62826	Q9UIA9
PDB IDs		1I2M 1IBR 1K5D 1K5G 1QBK 1RRP 3CH5 3EA5 3GJ0 3GJ3 3GJ4 3GJ5 3GJ6 3GJ7 3GJ8 3GJX 3NBY 3NBZ 3NC0 3NC1 3ZJY 4GMX 4GPT 4HAT 4HAU 4HAV 4HAW 4HAX 4HAY 4HAZ 4HB0 4HB2 4HB3 4HB4
Enriched GO Terms of Interacting Partners?		Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Intracellular Transport Protein Transport Establishment Of Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Nuclear Import Protein Localization Cellular Localization Protein Localization To Nucleus Protein Import Into Nucleus Viral Process Cellular Protein Localization Protein Import Establishment Of Protein Localization To Organelle RNA Transport RNA Localization Protein Localization To Organelle Protein Targeting Protein Export From Nucleus Nuclear Export Transport Ribosomal Protein Import Into Nucleus Positive Regulation Of Ran GTPase Activity Viral Life Cycle MRNA Transport Cellular Response To Organic Substance Mitotic Cell Cycle Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly NLS-bearing Protein Import Into Nucleus Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Response To Organic Substance Regulation Of Nucleocytoplasmic Transport Cell Cycle Positive Regulation Of Metabolic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Process Nuclear Envelope Organization Mitotic Cell Cycle Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Protein Export From Nucleus Intracellular Transport Of Virus Regulation Of Intracellular Transport Cellular Response To Transforming Growth Factor Beta Stimulus Viral Transcription	Cytoplasmic Transport Nucleocytoplasmic Transport Nuclear Transport Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Nuclear Export Establishment Of Localization In Cell RNA Transport RNA Localization Cellular Localization Intracellular Transport Of Virus Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Intracellular Protein Transport Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway RNA Export From Nucleus Toll-like Receptor 4 Signaling Pathway JNK Cascade Immune Response-regulating Signaling Pathway Toll-like Receptor Signaling Pathway Cellular Protein Localization TRNA Export From Nucleus Negative Regulation Of RNA Export From Nucleus Golgi Vesicle Docking Viral Penetration Into Host Nucleus Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade MRNA Transport Cellular Response To Growth Factor Stimulus Nuclear Import Response To Growth Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Immune Response Ribosomal Small Subunit Export From Nucleus Activation Of Innate Immune Response Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle
Tagcloud ?		5a accessible actually arginine bandshift bi cargo characterised directional dissociated export exports gtpase heterodimer import imported importin localisation masks multimeric nes nls nucleoplasm overlaps rab rev rip shuttle unspliced	abundant accumulated condensation culminating cytoplasm dense enucleation erythroblasts erythroid erythropoiesis export exportin extruded facilitated fetal h2a hemoglobin histones involves knockdown late maturation migrated nuclear nuclei otherwise proteomic striking strikingly
Tagcloud (Difference) ?		5a accessible actually arginine bandshift bi cargo characterised directional dissociated exports gtpase heterodimer import imported importin localisation masks multimeric nes nls nucleoplasm overlaps rab rev rip shuttle unspliced	abundant accumulated condensation culminating cytoplasm dense enucleation erythroblasts erythroid erythropoiesis exportin extruded facilitated fetal h2a hemoglobin histones involves knockdown late maturation migrated nuclear nuclei otherwise proteomic striking strikingly
Tagcloud (Intersection) ?		export