RAD23A and EWSR1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAD23A	EWSR1
Gene Name		RAD23 homolog A (S. cerevisiae)	EWS RNA-binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Proteasome Complex Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	Damaged DNA Binding Single-stranded DNA Binding Protein Binding Polyubiquitin Binding Ubiquitin-specific Protease Binding	Nucleotide Binding RNA Binding Protein Binding Calmodulin Binding Zinc Ion Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Nucleotide-excision Repair Viral Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Viral Genome Replication	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		50 interactors: A2M ADRM1 ANKRD40 ATXN3 ATXN7 CCNA2 CCNB1 CDC37 CREBBP DBI ECSIT EP300 EWSR1 FAM188A FILIP1 GTF2H1 IFIT3 IFIT5 LOXL4 MAST1 MDM2 MPG NGLY1 PARK2 PDE6D PHAX PI4K2A PSEN1 PSMC5 PSMD4 RNF115 RNF32 RPN1 SQSTM1 TRAF2 TRAF5 TRIM54 TRIP6 UBB UBE2D1 UBE2L3 UBE2L6 UBE3A UBL7 UBQLN4 USP25 VAV2 XPC ZBTB44 ZBTB8A	159 interactors: ACTL6A AGT ATN1 ATPAF2 ATXN3 BAD BARD1 BLZF1 BNIP3L BTK C10orf12 C11orf16 C19orf57 CALM1 CCDC91 CD177 CDK12 CEACAM5 CETP CFDP1 CHERP CNST CPSF6 CPSF7 CREBBP CUEDC2 CXADR DFFA DHX9 DMRTB1 DNAJB3 DYNLL2 E2F8 ECD ELAVL3 ELAVL4 ELK1 EP300 EPAS1 EPT1 ERCC5 FAM131C FASN FLI1 FUS FXR2 GNPDA1 GPBP1L1 HBP1 HDAC3 HERPUD1 HIST1H2BN HLTF HMGA1 HMGN4 HNRNPUL1 HSPA2 IRF3 ITCH ITGB5 JUN KCNMB1 KEL KHDRBS2 KRR1 KXD1 LILRA3 MAGEA11 MAPK1IP1L MATK MDFI MNS1 MRPS18B MSC MTCP1 MTMR9 MVK MYL6 MYO1F MYOZ2 NBPF3 NDRG1 NDUFB1 NDUFV1 NINL NLE1 NONO NPPB NSUN4 NTNG2 PCBP1 PDHX PEF1 PGLS PLSCR1 POLR2G POLR3A POU4F1 POU5F1 PRKCA PRMT1 PRR13 PRRC2A PRTFDC1 PRUNE2 PTK2B RAB37 RAD23A RALYL RASL11B RBPMS RFX3 RHOXF2 RMND5B RNF183 RPL31 RPS15A SALL2 SCMH1 SEC24A SEC24D SERP2 SF1 SF3B4 SLC1A1 SLC22A24 SMAD1 SMAD4 SNRPC SSBP2 SSBP3 SUPT4H1 SUV39H2 TAF1 TFG TMSB4Y TONSL TPGS2 TRAF1 TRAF2 TRAF3 TRIM37 TRIM5 TRPV5 TSPAN3 TULP2 USP7 VPS72 WBP4 WDR37 WWP1 WWP2 YWHAG YY1AP1 ZBTB1 ZDHHC3 ZNF165 ZNF184 ZNF383
Entrez ID		5886	2130
HPRD ID		07191	00592
Ensembl ID		ENSG00000179262	ENSG00000182944
Uniprot IDs		A8K1J3 P54725	Q01844
PDB IDs		1DV0 1F4I 1IFY 1OQY 1P98 1P9D 1QZE 1TP4 1ZO6 2WYQ	2CPE
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Catabolic Process Protein Polyubiquitination Regulation Of Protein Catabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Metabolic Process Cellular Response To Stress Response To Stress Cellular Protein Modification Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Ligase Activity Positive Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Checkpoint Mitotic DNA Damage Checkpoint Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Mitotic DNA Integrity Checkpoint Cellular Response To Oxygen Levels Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Catalytic Activity Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cellular Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Innate Immune Response	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Viral Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter RNA Processing Negative Regulation Of Gene Expression Cellular Response To Stress Regulation Of Establishment Of Protein Localization Negative Regulation Of Transcription, DNA-templated MRNA Metabolic Process MRNA Processing Apoptotic Process Regulation Of Intracellular Transport Response To Virus Programmed Cell Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Regulation Of Cellular Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Transport Immune System Process Regulation Of Protein Localization Cell Death Defense Response Death Regulation Of Cell Death
Tagcloud ?		2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase	arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1
Tagcloud (Difference) ?		2h5 accompanies anova dynactin gadd45a gtf2h5 invites keuls macaques malfunctioning nbn1 ndd ndds newman ovx perimenopausal presenilin1 proteosome psen1 raphe scna serotonin speculation subserving symptomology ube2d3 ube3a ubea5 ubiquinase	arranged blue cauda cd99 cords equina focal fusion glomus hybridization immunophenotypic indolent infrequent involving ki labeling longstanding mitoses nerve nests neu reverse roots rosette round smooth spinal transcriptase wt1
Tagcloud (Intersection) ?