DMRT3 and KHDRBS3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DMRT3	KHDRBS3
Gene Name		doublesex and mab-3 related transcription factor 3	KH domain containing, RNA binding, signal transduction associated 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity	RNA Binding Protein Binding SH3 Domain Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 23377640)
Protein-Protein Interactions		26 interactors: CCNDBP1 INCA1 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 MDFI MGAT5B MID2 MTUS2 NOTCH2NL PLSCR1 PSMA3 RBPMS REL SAT1 TCF4 TRAF1 TRIM23 TRIM27 TRIP6 UBASH3B	30 interactors: BAHD1 CACNA1A CCDC33 DMRT3 FUS HNRNPC HNRNPK INPP5D KHDRBS1 KHDRBS2 LNX1 MARK4 NCOA5 NELFB NUDT18 PRMT1 PRPF31 PSMF1 PTBP2 RBBP6 RBM7 RBMX RBMY1A1 SGSM2 SIAH1 SNRPC SRSF9 U2AF2 YTHDC1 ZNF408
Entrez ID		58524	10656
HPRD ID		16827	10007
Ensembl ID		ENSG00000064218	ENSG00000131773
Uniprot IDs		Q9NQL9	O75525
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Viral Process Regulation Of Intracellular Protein Transport Regulation Of Signaling Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Transferase Activity Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Establishment Of Protein Localization Regulation Of Protein Metabolic Process Regulation Of Viral Process Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Positive Regulation Of Intracellular Transport Regulation Of Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Cellular Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Phosphorylation Regulation Of Viral Transcription Spermidine Acetylation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway	MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Negative Regulation Of RNA Splicing Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Splicing MRNA Splice Site Selection Spliceosomal Complex Assembly Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Regulation Of MRNA Processing Metabolic Process Regulation Of Metabolic Process Ribonucleoprotein Complex Biogenesis Regulation Of Gene Expression Transcription, DNA-templated Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Component Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Positive Regulation Of RNA Splicing Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Cerebellar Molecular Layer Development DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Adult Walking Behavior Cellular Process Cellular Macromolecule Biosynthetic Process Ventral Spinal Cord Development Transmission Of Nerve Impulse Macromolecule Biosynthetic Process Vestibular Nucleus Development
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