PTPN3 and DIP2A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTPN3	DIP2A
Gene Name		protein tyrosine phosphatase, non-receptor type 3	DIP2 disco-interacting protein 2 homolog A (Drosophila)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Cytoplasmic Side Of Plasma Membrane	Nucleus Cell Surface
	Molecular Function	Phosphotyrosine Binding Protein Tyrosine Phosphatase Activity Protein Binding Cytoskeletal Protein Binding Sodium Channel Regulator Activity ATPase Binding	Catalytic Activity Protein Binding Transcription Factor Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Membrane Protein Ectodomain Proteolysis Liver Regeneration Regulation Of Membrane Depolarization During Action Potential Regulation Of Sodium Ion Transmembrane Transporter Activity	Multicellular Organismal Development Metabolic Process Negative Regulation Of Gene Expression Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ADAM17 AKR1C1 CD247 DIP2A GHR LMO1 NXT2 VCP WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10	18 interactors: ADAMTSL4 AES CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TMCC2 TRIM39 TRIP13 ZBTB43
Entrez ID		5774	23181
HPRD ID		06767	07611
Ensembl ID		ENSG00000070159	ENSG00000160305
Uniprot IDs		B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3	Q14689 Q96NX2
PDB IDs		2B49
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Cellular Response To Hormone Stimulus Regulation Of Mitochondrion Organization Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Signal Transduction Apoptotic Signaling Pathway Regulation Of Apoptotic Process JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Peptide Hormone Growth Hormone Receptor Signaling Pathway Regulation Of Cell Death Cellular Response To Organonitrogen Compound Cellular Response To Growth Hormone Stimulus Response To Hormone Response To Peptide Apoptotic Process Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Cell Death Positive Regulation Of Apoptotic Signaling Pathway Death Response To Growth Hormone Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Cell Death Positive Regulation Of Intracellular Transport Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Regulation Of Protein Kinase Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Protein Transport Signaling T Cell Differentiation In Thymus Regulation Of Kinase Activity Cell Communication Establishment Of Protein Localization Response To Organonitrogen Compound Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Metabolic Process Beta Selection Positive Regulation Of Protein Modification Process	Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Regulation Of Cellular Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Proteolysis Negative Regulation Of Protein Binding Regulation Of Signaling Regulation Of Wnt Signaling Pathway Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Protein Metabolic Process Leading Edge Cell Differentiation Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Binding Negative Regulation Of Protein Ubiquitination Apoptotic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Clathrin-mediated Endocytosis Programmed Cell Death Negative Regulation Of Protein Catabolic Process Cell Death Death Cerebral Cortex GABAergic Interneuron Fate Commitment Liver Regeneration Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Membrane Depolarization During Action Potential Positive Regulation Of Early Endosome To Late Endosome Transport Branching Morphogenesis Of A Nerve Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Binding Organ Development Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment
Tagcloud ?		adaptor advance border cascades dephosphorylation doi dptpmeg drosophila egfr endocytosis eps15 ferm homolog impairs lysosomal morphogenesis onc oncogene online pdz publication raft scaffolding september suppress trafficking tumorigenicity wing xenograft
Tagcloud (Difference) ?		adaptor advance border cascades dephosphorylation doi dptpmeg drosophila egfr endocytosis eps15 ferm homolog impairs lysosomal morphogenesis onc oncogene online pdz publication raft scaffolding september suppress trafficking tumorigenicity wing xenograft
Tagcloud (Intersection) ?