MYH7B and SMYD1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		MYH7B	SMYD1
Gene Name		myosin, heavy chain 7B, cardiac muscle, beta	SET and MYND domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Myosin Filament	Nucleus Cytoplasm
	Molecular Function	Motor Activity Actin Binding Protein Binding ATP Binding	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding
	Biological Process	Metabolic Process	Chromatin Remodeling Transcription, DNA-templated Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Prothrombin time ( 22703881)
Protein-Protein Interactions		1 interactors: SMYD1	19 interactors: ADSS BHLHE40 C11orf16 C11orf53 CCDC113 FAM204A H3F3C HDAC2 HDAC3 HOMEZ LENG8 MYH7B NACA OGDHL RBM4B TTC33 UTP14A WDR77 ZBTB44
Entrez ID		57644	150572
HPRD ID		11379	06025
Ensembl ID		ENSG00000078814	ENSG00000115593
Uniprot IDs		A7E2Y1	E9PHG3 Q5HYE8 Q8NB12
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Myoblast Differentiation Positive Regulation Of Myotube Differentiation Regulation Of Myoblast Differentiation Regulation Of Myotube Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Histone Lysine Methylation Peptidyl-lysine Methylation Regulation Of Striated Muscle Cell Differentiation Histone Methylation Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Regulation Of Muscle Cell Differentiation Protein Methylation Chromatin Remodeling	Circadian Regulation Of Gene Expression Circadian Rhythm RNA Metabolic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4 Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Histone H3 Deacetylation Nitrogen Compound Metabolic Process Histone H3-K9 Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Regulation Of Developmental Growth Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Response To Ammonium Ion Regulation Of Striated Muscle Cell Differentiation RNA Biosynthetic Process Regulation Of Circadian Rhythm Maintenance Of Chromatin Silencing 'de Novo' AMP Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression Response To Abiotic Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development AMP Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Muscle Cell Differentiation Aspartate Metabolic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Morphogenesis
Tagcloud ?		1q21 advance afg3l1p analyzing arnt august casp8 cdk10 clptm1l dermatology doi fto germline integrating investigative jid journal mitf mtap mx2 pla2g6 proxies publication retrieving slc45a2 supplementary synopsis tagged updated	adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Difference) ?		1q21 advance afg3l1p analyzing arnt august casp8 cdk10 clptm1l dermatology doi fto germline integrating investigative jid journal mitf mtap mx2 pla2g6 proxies publication retrieving slc45a2 supplementary synopsis tagged updated	adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Intersection) ?