PRM1 and LBR

Number of citations of the paper that reports this interaction (PMID 14701833)
8

Data Source:
HPRD (in vitro)

		PRM1	LBR
Gene Name		protamine 1	lamin B receptor
Image
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleoplasm	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	DNA Binding	DNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Poly(A) RNA Binding Chromo Shadow Domain Binding
	Biological Process	DNA Packaging Multicellular Organismal Development Spermatogenesis Cell Differentiation Chromosome Condensation	Cholesterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways			Cholesterol biosynthesis Metabolism of lipids and lipoproteins
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Multiple sclerosis ( 22190364) Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: LBR SRPK1	11 interactors: AKAP8L CBX3 CBX5 FNBP4 HIST1H3A HIST2H4A LMNB1 MECP2 PRM1 SRPK1 YWHAG
Entrez ID		5619	3930
HPRD ID		01688	02488
Ensembl ID		ENSG00000175646	ENSG00000143815
Uniprot IDs		P04553 Q3MN80	Q14739
PDB IDs		2AWR	2DIG
Enriched GO Terms of Interacting Partners?			Chromatin Silencing DNA Packaging Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Chromatin Organization DNA Replication-dependent Nucleosome Assembly Gene Silencing DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Methylation DNA Modification DNA Metabolic Process Nucleosome Assembly Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Catecholamine Secretion Chromatin Modification Chromatin Assembly Or Disassembly Negative Regulation Of Megakaryocyte Differentiation Proprioception Protein-DNA Complex Assembly Regulation Of Synaptic Plasticity Chromatin Remodeling Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Sperm Chromatin Condensation Regulation Of RNA Metabolic Process Cardiolipin Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Respiratory Gaseous Exchange By Neurological System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Neuromuscular Process Controlling Posture Regulation Of Synaptic Transmission Regulation Of Respiratory System Process Regulation Of Gene Expression Glucocorticoid Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		adhered appressed arrested asexual calcium crassa dataset deltalfd deltaprm1 encode fig filamentous fringe fungal fungus fusion germinated germling germlings golgi hyphae interconnected lfd lysis merger neurospora somatic spores tightly	absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Difference) ?		adhered appressed arrested asexual calcium crassa dataset deltalfd deltaprm1 encode fig filamentous fringe fungal fungus fusion germinated germling germlings golgi hyphae interconnected lfd lysis merger neurospora somatic spores tightly	absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Intersection) ?