ERBB2IP and ITGB4

Number of citations of the paper that reports this interaction (PMID 11375975)
11

Data Source:
HPRD (in vitro, two hybrid)

		ERBB2IP	ITGB4
Gene Name		erbb2 interacting protein	integrin, beta 4
Image
Gene Ontology Annotations	Cellular Component	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane	Basement Membrane Plasma Membrane Integrin Complex Basal Plasma Membrane Cell Surface Hemidesmosome Cell Leading Edge Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding	G-protein Coupled Receptor Binding Receptor Activity Protein Binding
	Biological Process	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Autophagy Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Response To Wounding Extracellular Matrix Organization Hemidesmosome Assembly Cell Junction Assembly Nail Development Skin Development Filopodium Assembly Mesodermal Cell Differentiation Digestive Tract Development Cell Motility Renal System Development Amelogenesis
Pathways		Signaling by ERBB2	Cell junction organization Syndecan interactions Type I hemidesmosome assembly Collagen formation Laminin interactions Non-integrin membrane-ECM interactions Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9	23 interactors: ALOX12 ATXN1 CLCA1 CLCA2 COL17A1 DST EIF6 ERBB2 ERBB2IP FYN GRB2 ITGA6 MET PLEC PRKCA PRKCD PTK2 SHC1 SREBF2 VIM YES1 YWHAB YWHAQ
Entrez ID		55914	3691
HPRD ID		06090	00946
Ensembl ID		ENSG00000112851	ENSG00000132470
Uniprot IDs		B4DIP2 Q96RT1	P16144
PDB IDs		1MFG 1MFL 1N7T 2H3L 2QBW 3CH8	1QG3 2YRZ 3F7P 3F7Q 3F7R 3FQ4 3FSO 3H6A
Enriched GO Terms of Interacting Partners?		Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Fibroblast Growth Factor Receptor Signaling Pathway Response To Wounding Cellular Response To Fibroblast Growth Factor Stimulus Hemidesmosome Assembly Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Response To Growth Factor Wound Healing Regulation Of Cell Adhesion Peptidyl-tyrosine Phosphorylation Blood Coagulation Hemostasis Locomotion Immune Response-regulating Signaling Pathway Platelet Activation Protein Autophosphorylation Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Chemotaxis Axon Guidance Leukocyte Migration Cell Motility Positive Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Phosphorylation Apoptotic Process Cell-substrate Junction Assembly Regulation Of Cell Activation Programmed Cell Death Cell Death Death Cellular Response To Peptide Hormone Stimulus Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Organic Substance Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Platelet Aggregation Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway
Tagcloud ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2
Tagcloud (Difference) ?		adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer	bag1 bcl2l2 bctis ccna2 comprehend ctsb deregulations fgf1 fosl1 gabrp gsn hnepi id2 il6r klf5 klk5 map2k7 microdissected ngfb ngfr ontological pappa plau scgb1d2 scgb2a1 serpinb5 serpine1 thbs1 thbs2
Tagcloud (Intersection) ?