ATF7IP and ZBTB6

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ATF7IP	ZBTB6
Gene Name		activating transcription factor 7 interacting protein	zinc finger and BTB domain containing 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding ATPase Activity	DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	5 interactors: ATF7IP SKIL SUMO1 SUMO1P1 ZBTB26
Entrez ID		55729	10773
HPRD ID		09811	09341
Ensembl ID		ENSG00000171681	ENSG00000186130
Uniprot IDs		B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6	Q15916
PDB IDs		2RPQ
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process PML Body Organization Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Localization To Nuclear Pore Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Localization To Nuclear Envelope Regulation Of Transcription, DNA-templated Regulation Of Protein Complex Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Protein Heterotrimerization Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Protein Homotrimerization Transcription, DNA-templated Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Regulation Of DNA-templated Transcription, Initiation RNA Biosynthetic Process Protein Sumoylation Response To Cytokine Lens Fiber Cell Differentiation Protein Trimerization Negative Regulation Of Transcription From RNA Polymerase II Promoter Blastocyst Formation Negative Regulation Of DNA Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors RNA Metabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Metabolic Process Response To Antibiotic DNA Methylation Gene Expression Positive Regulation Of Response To DNA Damage Stimulus Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process DNA Metabolic Process
Tagcloud ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?