PRKAB2 and KRTAP10-7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRKAB2	KRTAP10-7
Gene Name		protein kinase, AMP-activated, beta 2 non-catalytic subunit	keratin associated protein 10-7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol AMP-activated Protein Kinase Complex	Keratin Filament
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding Identical Protein Binding
	Biological Process	Energy Reserve Metabolic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Regulation Of Protein Kinase Activity Membrane Organization
Pathways		Organelle biogenesis and maintenance Integration of energy metabolism Metabolism of lipids and lipoproteins Regulation of Rheb GTPase activity by AMPK IRS-mediated signalling mTOR signalling Translocation of GLUT4 to the plasma membrane Import of palmitoyl-CoA into the mitochondrial matrix mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade Signaling by Insulin receptor Fatty acid, triacylglycerol, and ketone body metabolism Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-related events Mitochondrial biogenesis IRS-mediated signalling Activation of PPARGC1A (PGC-1alpha) by phosphorylation Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) AMPK inhibits chREBP transcriptional activation activity PKB-mediated events PI3K Cascade
Drugs		Adenosine monophosphate
Diseases
GWAS
Protein-Protein Interactions		70 interactors: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CCDC36 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FAM208B FDX1 FLNC GATA1 GATAD2B GET4 GNB2L1 GOLGA2 GRN IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PRDM14 PRKAA1 PRKAA2 PRKAG1 PRKAG2 PRKAG3 PSME3 PYGM RBPMS REL RHEBL1 RIMBP3 SPRY2 STX11 STX19 TADA2A TCF4 TP53BP2 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32	215 interactors: AEN AES ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BUD31 BYSL C16orf59 C19orf57 C19orf66 C8orf33 C9orf9 CARHSP1 CARKD CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 COL8A1 CRCT1 CREB5 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 DAAM2 DERL2 DHX57 DMRT3 E2F6 E4F1 EHHADH FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HHEX HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3E LCE4A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MOBP MRGBP MXD3 MXI1 NAA10 NOL12 NOTCH2NL NPBWR2 NPDC1 NUBP2 NUDCD3 NUFIP2 P2RY6 PCED1A PCSK5 PDIA5 PDLIM5 PFKL PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PTGDS PTGER3 PTPMT1 PVR PVRL2 PVRL3 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STK16 SUV39H1 TAPBPL TCEA2 TCEANC THAP1 THAP6 TMA16 TMEM8A TNP2 TNS2 TOR1A TREX1 TRIM42 TULP3 TXNDC5 TYRO3 UCP2 UXT VTI1B WDYHV1 WNT11 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF101 ZNF124 ZNF133 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF26 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF41 ZNF417 ZNF418 ZNF419 ZNF425 ZNF433 ZNF439 ZNF490 ZNF543 ZNF555 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF697 ZNF707 ZNF778 ZNF792 ZNF846 ZNHIT1 ZSCAN26
Entrez ID		5565	386675
HPRD ID		04117	11193
Ensembl ID		ENSG00000131791	ENSG00000205441
Uniprot IDs		O43741	P60409
PDB IDs		2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2Y94 2YA3 4EAI 4EAJ
Enriched GO Terms of Interacting Partners?		Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Arrest Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Glycogen Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Glycolytic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Cell Cycle Energy Reserve Metabolic Process Regulation Of Cell Cycle Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Cellular Macromolecule Biosynthetic Process Polysaccharide Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Organelle Organization Gene Expression Cell Cycle Process Positive Regulation Of Phosphorylation RNA Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Protein Metabolic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Signaling Fatty Acid Biosynthetic Process Cellular Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Regulation Of Binding Regulation Of Metabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Phosphorylation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Cell Death	RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Cellular Metabolic Process Cellular Process Regulation Of Metabolic Process Regulation Of Cellular Process Susceptibility To T Cell Mediated Cytotoxicity Transepithelial Transport Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Keratinization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Gene Expression Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Penetration Of Zona Pellucida Negative Regulation Of Transcription From RNA Polymerase II Promoter Spinal Cord Dorsal/ventral Patterning Positive Regulation Of Immune Response To Tumor Cell Multicellular Organismal Development Spinal Cord Patterning Negative Regulation Of Cellular Metabolic Process Respiratory Tube Development
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