PPP2R2A and STRN3

Number of citations of the paper that reports this interaction (PMID 10681496)
30

Data Source:
HPRD (in vivo)

		PPP2R2A	STRN3
Gene Name		protein phosphatase 2, regulatory subunit B, alpha	striatin, calmodulin binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleoplasm Cytosol	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane Dendrite Neuronal Cell Body Protein Complex
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase Type 2A Regulator Activity	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Calmodulin Binding Protein Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Mitotic Cell Cycle Protein Dephosphorylation Mitotic Nuclear Envelope Reassembly Signal Transduction Gene Expression Response To Morphine Regulation Of Catalytic Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Estradiol Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Nonsense-Mediated Decay (NMD) G1 Phase G2/M Transition Mitotic Anaphase Cell Cycle, Mitotic M Phase Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Cyclin D associated events in G1 Cyclin A/B1 associated events during G2/M transition Nuclear Envelope Reassembly Initiation of Nuclear Envelope Reformation Mitotic G2-G2/M phases Mitotic G1-G1/S phases Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS		Height ( 23563607)
Protein-Protein Interactions		12 interactors: ATR CHEK2 GRIN1 GRIN2D MTOR NDRG1 PPP2CA PPP2R1A PPP2R1B RRN3 STRN3 TGFBR1	6 interactors: CALM1 MOB1A PPP2R1A PPP2R1B PPP2R2A SLC2A4
Entrez ID		5520	29966
HPRD ID		09223	11613
Ensembl ID		ENSG00000221914	ENSG00000196792
Uniprot IDs		P63151	Q13033
PDB IDs		3DW8
Enriched GO Terms of Interacting Partners?		Regulation Of DNA Replication Regulation Of Signaling Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Mitotic Nuclear Envelope Reassembly Regulation Of Signal Transduction Nuclear Envelope Reassembly Positive Regulation Of Transcription, DNA-templated Peptidyl-serine Phosphorylation Nucleus Organization Replicative Senescence Positive Regulation Of Macromolecule Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Gene Expression Double-strand Break Repair Negative Regulation Of JAK-STAT Cascade Positive Regulation Of Cellular Biosynthetic Process Apoptotic Process Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Startle Response Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Process Regulation Of Intracellular Signal Transduction Cell Death Regulation Of Cellular Response To Heat Death Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Response To Fibroblast Growth Factor Negative Regulation Of Signal Transduction Inactivation Of MAPK Activity Cell Development Response To Abiotic Stimulus Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Intracellular Signal Transduction Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Regulation Of Cellular Component Organization Negative Regulation Of Signaling Positive Regulation Of Cell Death Developmental Process Synaptic Transmission, Glutamatergic	Mitotic Nuclear Envelope Reassembly Nuclear Envelope Reassembly Membrane Organization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Nuclear Envelope Organization Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Amylopectin Biosynthetic Process G2/M Transition Of Mitotic Cell Cycle Nucleus Organization Peptidyl-serine Dephosphorylation Second-messenger-mediated Signaling Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Response To Organonitrogen Compound RNA Catabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Fibroblast Growth Factor Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Pathogenesis Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Organic Substance Protein Dephosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Glucose Import Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Protein Phosphorylation Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Phosphorylation Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Endomembrane System Organization Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation
Tagcloud ?		22q13 alterations analyzing brca1 candidates computational developments drive driver estimates estimating generations genomes genomic identifies instability lineage mutator mutators neutral passenger passengers prkdc somatic take technologies throughput timing tumorigenesis
Tagcloud (Difference) ?		22q13 alterations analyzing brca1 candidates computational developments drive driver estimates estimating generations genomes genomic identifies instability lineage mutator mutators neutral passenger passengers prkdc somatic take technologies throughput timing tumorigenesis
Tagcloud (Intersection) ?