PPID and FES

Number of citations of the paper that reports this interaction (PMID 9222609)
41

Data Source:
BioGRID (pull down)

		PPID	FES
Gene Name		peptidylprolyl isomerase D	FES proto-oncogene, tyrosine kinase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Cytoplasm Golgi Apparatus Cytosol Focal Adhesion Microtubule Cytoskeleton Cytoplasmic Membrane-bounded Vesicle Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Transcription Factor Binding Cyclosporin A Binding Estrogen Receptor Binding Hsp70 Protein Binding Heat Shock Protein Binding Hsp90 Protein Binding	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Immunoglobulin Receptor Binding Phosphatidylinositol Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Peptidyl-prolyl Isomerization Protein Folding Protein Complex Assembly Apoptotic Process Protein Transport Viral Release From Host Cell Lipid Particle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Viral Genome Replication Positive Regulation Of Protein Secretion Chaperone-mediated Protein Folding Cellular Response To UV-A	Protein Phosphorylation Chemotaxis Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Axon Guidance Cell Proliferation Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Cell Migration Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Positive Regulation Of Microtubule Polymerization Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Regulation Of Mast Cell Degranulation Innate Immune Response Regulation Of Cell Differentiation Positive Regulation Of Myeloid Cell Differentiation Protein Autophosphorylation Regulation Of Vesicle-mediated Transport Regulation Of Cell Motility Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways			Signaling by SCF-KIT Axon guidance Semaphorin interactions Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling
Drugs
Diseases
GWAS			Blood pressure ( 21909110) Diastolic blood pressure ( 21909115) Hypertension ( 21909115) Systolic blood pressure ( 21909115)
Protein-Protein Interactions		20 interactors: APP BCL2 CSNK2B ESR1 FBXO25 FES HAP1 HSF1 HSP90AA1 HSP90AB1 HSPA8 KAT7 LNX1 PLK1 S100A1 S100A2 S100A6 SLC25A4 SMURF2 TRIM27	31 interactors: BCAR1 BCR CSF2RB DOK1 DPYSL5 EGFR FKBP4 FKBP5 HSH2D HSPA4 IL4R IRS1 IRS2 JAK1 JAK2 JAK3 MDFI NEDD4 PDE4DIP PIK3R1 PLXNA1 POT1 PPID PTGES3 RASA1 RASA3 STAT3 TERF1 TRIM28 ZNF746 ZNF775
Entrez ID		5481	2242
HPRD ID		11875	01814
Ensembl ID		ENSG00000171497	ENSG00000182511
Uniprot IDs		E5KN55 Q08752	P07332
PDB IDs			1WQU 2DCR 3BKB 3CBL 3CD3 4DYL 4E93
Enriched GO Terms of Interacting Partners?		Axonogenesis Regulation Of Cellular Response To Heat Axon Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Cell Projection Organization Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cellular Response To Heat Neuron Development Cellular Protein Metabolic Process Axon Guidance Cell Morphogenesis Neuron Differentiation Generation Of Neurons Regulation Of Binding Response To Heat Negative Regulation Of Cellular Metabolic Process Neurogenesis Nervous System Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Ubiquitination Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Protein Binding Cell Development Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Chemotaxis Protein Modification By Small Protein Conjugation Protein Metabolic Process Cellular Protein Modification Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Movement Of Cell Or Subcellular Component Cellular Response To Stimulus Positive Regulation Of Cell Cycle Phase Transition Response To Temperature Stimulus Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Organelle Organization Regulation Of Calcium Ion Transport Intracellular Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process System Development Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Innate Immune Response	Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Response To Growth Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Organonitrogen Compound Cellular Response To Peptide JAK-STAT Cascade Positive Regulation Of Transport Intracellular Signal Transduction Cellular Response To Hormone Stimulus Regulation Of Cellular Localization Regulation Of Cell Migration Signal Transduction Regulation Of Protein Transport Regulation Of Cell Motility Regulation Of Immune Response Response To Peptide Hormone Cellular Response To Stimulus Response To Organic Substance Regulation Of Establishment Of Protein Localization Regulation Of Locomotion Response To Peptide Regulation Of Cellular Component Movement Response To Stimulus Response To Hormone Positive Regulation Of Protein Transport Cellular Response To Organic Substance Signaling Regulation Of Cell Death Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Nucleocytoplasmic Transport Neurotrophin TRK Receptor Signaling Pathway Cell Communication Neurotrophin Signaling Pathway Regulation Of Protein Localization Response To Organonitrogen Compound Response To Stress Cytokine-mediated Signaling Pathway Chaperone-mediated Protein Folding Insulin Receptor Signaling Pathway Protein Import Epidermal Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification ERBB Signaling Pathway Locomotion
Tagcloud ?		accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules nrip1 obtain omnibus osteoprotegerin packages searched software vdr	1d4 counterpart e1c3 electrophoretic epsilon germline heavy hela iepsilon immunoglobulin initiating irs jak1 jak3 lysates mediating mobility parental promotor pronounced radiolabeled reconstitution restored shift stat6 tyrosine undergo utilized utilizing
Tagcloud (Difference) ?		accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules nrip1 obtain omnibus osteoprotegerin packages searched software vdr	1d4 counterpart e1c3 electrophoretic epsilon germline heavy hela iepsilon immunoglobulin initiating irs jak1 jak3 lysates mediating mobility parental promotor pronounced radiolabeled reconstitution restored shift stat6 tyrosine undergo utilized utilizing
Tagcloud (Intersection) ?