RBFOX1 and GCA

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBFOX1	GCA
Gene Name		RNA binding protein, fox-1 homolog (C. elegans) 1	grancalcin, EF-hand calcium binding protein
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network	Cytoplasm Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding	Calcium-dependent Cysteine-type Endopeptidase Activity Calcium Ion Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	MRNA Processing RNA Splicing Regulation Of RNA Splicing RNA Transport Neuromuscular Process Controlling Balance	Proteolysis Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Refractive error ( 23396134 23474815)
Protein-Protein Interactions		33 interactors: ALG13 ATN1 ATXN1 ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 KIFAP3 LZTS2 MAGED1 NOC2L NUMBL PCBP4 PRR20A PRRC2A PSMF1 QKI RBFOX2 RBM24 RBPMS RHOXF2 SNRPN TNIP1	5 interactors: ATXN1 LCP1 MAGEA8 RBFOX1 SRI
Entrez ID		54715	25801
HPRD ID		16091	06122
Ensembl ID		ENSG00000078328
Uniprot IDs		B7Z1U7 F5H0M1 Q59HD3 Q9NWB1	P28676
PDB IDs		2ERR	1F4O 1F4Q 1K94 1K95
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Cellular Process RNA Splicing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of RNA Splicing Cellular Macromolecule Biosynthetic Process Negative Regulation Of Signaling Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cell Migration In Hindbrain Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Canonical Wnt Signaling Pathway Hindbrain Development Biosynthetic Process Circadian Rhythm Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression MRNA Processing Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Calcium-dependent Cell-cell Adhesion Positive Regulation Of Photoreceptor Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cerebellum Morphogenesis Regulation Of MRNA Stability Hindbrain Morphogenesis Regulation Of RNA Stability Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Metabolic Process	Intracellular Sequestering Of Iron Ion Protein Kinase A Signaling Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Intracellular Protein Transport Regulation Of Membrane Potential Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Relaxation Of Muscle Negative Regulation Of Heart Rate Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sequestering Of Metal Ion Regulation Of Cell Communication By Electrical Coupling
Tagcloud ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	acanthamoeba acquisition agc ancestral arrays cag clustering coevolution coincided duplications enlargement evolutionary falciparum incorporate insects lineages metazoans motifs nematodes opa overrepresented propensity ribosomal rnas slippage tbp underrepresentation vertebrates wheat
Tagcloud (Difference) ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	acanthamoeba acquisition agc ancestral arrays cag clustering coevolution coincided enlargement evolutionary falciparum incorporate insects lineages metazoans motifs nematodes opa overrepresented propensity ribosomal rnas slippage tbp underrepresentation vertebrates wheat
Tagcloud (Intersection) ?		duplications