PLEKHA5 and PPP1R13B

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		PLEKHA5	PPP1R13B
Gene Name		pleckstrin homology domain containing, family A member 5	protein phosphatase 1, regulatory subunit 13B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Protein Binding Transcription Factor Binding
	Biological Process	Biological_process Reproductive System Development	Negative Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		30 interactors: ARHGEF9 BLOC1S6 CCDC186 CCDC88B CCDC92 CEP250 CEP350 DES EVPL EXTL3 KANSL1 KIF3A KRT19 KRT20 KTN1 LAMB2 LSM4 MAX PDZD11 PLEC PLEKHA6 PPP1R13B PROM1 SH3BP5L SOGA1 SPTAN1 SPTBN1 UPF1 WASH2P YWHAG	15 interactors: APC BRCA1 CCDC184 CDC5L CEP63 KHDRBS1 MIPOL1 PLEKHA5 PPP1CA PPP1CC TNIK TP63 TP73 TRAF1 UBC
Entrez ID		54477	23368
HPRD ID		09684	07345
Ensembl ID		ENSG00000052126	ENSG00000088808
Uniprot IDs		Q9HAU0	Q96KQ4
PDB IDs		2DKP
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Hemidesmosome Assembly Glomerular Visceral Epithelial Cell Differentiation Regulation Of Protein Complex Disassembly Cellular Localization Regulation Of Cellular Component Organization Movement Of Cell Or Subcellular Component Cellular Process Retina Development In Camera-type Eye Organelle Organization Generation Of Neurons Cell Differentiation Involved In Kidney Development Neuron Differentiation Cytoskeleton Organization Regulation Of Actin Filament Polymerization Microtubule-based Process Neurogenesis Metanephric Glomerular Basement Membrane Development Axon Extension Involved In Regeneration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Cell-substrate Junction Assembly Actin Filament Capping Membrane Organization Regulation Of Cytoskeleton Organization Glomerulus Development Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Depolymerization Epithelial Cell Differentiation Regulation Of Organelle Organization Metanephric Glomerular Visceral Epithelial Cell Development Response To Axon Injury Protein Localization Neuron Development Regulation Of Actin Filament Depolymerization Execution Phase Of Apoptosis Negative Regulation Of Actin Filament Polymerization Sensory Organ Development Glomerular Parietal Epithelial Cell Differentiation Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Centriole-centriole Cohesion Response To Insulin Establishment Of Localization In Cell Microtubule-based Movement Intracellular Transport Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport	Signal Transduction In Response To DNA Damage Cell Cycle Checkpoint Cell Cycle DNA Damage Checkpoint Negative Regulation Of Cell Cycle Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Cellular Response To DNA Damage Stimulus Regulation Of Signal Transduction Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process Signal Transduction Regulation Of Cell Cycle Cellular Response To Stress Regulation Of Signaling Signaling Signal Transduction By P53 Class Mediator Cell Communication Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Positive Regulation Of Signal Transduction Cell Division Cellular Response To Stimulus Response To Radiation Regulation Of Apoptotic Process Glycogen Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Death Apoptotic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Programmed Cell Death Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Death Death Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Polysaccharide Metabolic Process Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Positive Regulation Of Cell Death Mitotic DNA Damage Checkpoint
Tagcloud ?		a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul	acetylase acinic biomarkers cdkn2a damaging define deletions describe efforts ep300 exome future gland induces insights landscape malignancies massive mutational necessary nonsynonymous noted parotid presentation provides salivary sequencing underpinnings underwent
Tagcloud (Difference) ?		a375 a375br a375p aberrantly barrier bbb brain cerebrotropic constructed differentially extra homing immunofluorescence knock mediators melanoma metastases metastasis metastatic overwhelming parental passage profiles profiling propensity subjected transmigration viability yumul	acetylase acinic biomarkers cdkn2a damaging define deletions describe efforts ep300 exome future gland induces insights landscape malignancies massive mutational necessary nonsynonymous noted parotid presentation provides salivary sequencing underpinnings underwent
Tagcloud (Intersection) ?