SLC38A2 and STX11

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SLC38A2	STX11
Gene Name		solute carrier family 38, member 2	syntaxin 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex
	Molecular Function	Amino Acid Transmembrane Transporter Activity Symporter Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Ion Transport Sodium Ion Transport Amino Acid Transport Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion Transmembrane Transport	Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Membrane Neutrophil Degranulation Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Vesicle Docking Membrane Fusion
Pathways		Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane SLC-mediated transmembrane transport Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP STX11	62 interactors: AES APP BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 FHL5 GOLGA8EP GOLGA8F HAUS1 IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 STXBP1 SUV39H1 TAF6L TBK1 TCF4 TNFRSF21 USHBP1 VAMP2 VPS52 WDYHV1 ZCCHC10 ZNF417 ZNF587
Entrez ID		54407	8676
HPRD ID		05535	09231
Ensembl ID		ENSG00000134294
Uniprot IDs		Q96QD8	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Exocytosis Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Secretion By Cell Axon Choice Point Recognition Neutrophil Degranulation Cytotoxic T Cell Degranulation Secretion Neuron Remodeling Neutrophil Activation Involved In Immune Response Natural Killer Cell Degranulation Cell Activation Synaptic Vesicle Fusion To Presynaptic Membrane T Cell Mediated Cytotoxicity Innate Immune Response Cellular Copper Ion Homeostasis Neutrophil Mediated Immunity Neutrophil Activation Copper Ion Homeostasis Suckling Behavior Natural Killer Cell Activation Involved In Immune Response Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Adhesion T Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response RNA Polyadenylation Neuron Recognition Defense Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Leukocyte Degranulation Ionotropic Glutamate Receptor Signaling Pathway Vesicle-mediated Transport Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Vesicle Fusion Mating Neuromuscular Junction Development	Neurotransmitter Secretion Glutamate Secretion Vesicle Localization Regulation Of Neurotransmitter Levels Neurotransmitter Transport Gene Expression Organelle Localization Synaptic Vesicle Transport Establishment Of Vesicle Localization Establishment Of Organelle Localization Vesicle Organization Synaptic Vesicle Exocytosis Acid Secretion Energy Reserve Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Dicarboxylic Acid Transport Organelle Organization Membrane Docking Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Exocytosis RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Secretion By Cell Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of RNA Metabolic Process Viral Process Synaptic Vesicle Docking Membrane Fusion Axon Cargo Transport Synaptic Vesicle Priming Regulation Of Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Vesicle Fusion Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Generation Of Precursor Metabolites And Energy Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Macromolecule Biosynthetic Process Cellular Localization
Tagcloud ?		11betahsd2 alcohol alters awareness childbearing conception dawley drinking educate etoh falling fetuses glut1 glycogen igf2 junctional kdr labyrinth libitum pc periconceptional placenta placental placentas pregnancies sexes sprague unplanned vegfa	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Difference) ?		11betahsd2 alcohol alters awareness childbearing conception dawley drinking educate etoh falling fetuses glut1 glycogen igf2 junctional kdr labyrinth libitum pc periconceptional placenta placental placentas pregnancies sexes sprague unplanned vegfa	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Intersection) ?