ATP5B and ATP5A1

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (two hybrid, biochemical)

		ATP5B	ATP5A1
Gene Name		ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Proton-transporting ATP Synthase, Catalytic Core Mitochondrial Matrix Plasma Membrane Cell Surface Membrane Mitochondrial Membrane Mitochondrial Nucleoid Extracellular Vesicular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity Protein Binding ATP Binding ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding ATP Binding ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding Poly(A) RNA Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Angiogenesis Osteoblast Differentiation Generation Of Precursor Metabolites And Energy Lipid Metabolic Process ATP Biosynthetic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Organelle Organization Mitochondrion Organization ATP Hydrolysis Coupled Proton Transport Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process Regulation Of Intracellular PH	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process Embryo Development ATP Hydrolysis Coupled Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Organelle biogenesis and maintenance Mitochondrial protein import Transcriptional activation of mitochondrial biogenesis The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling Mitochondrial biogenesis	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Mitochondrial protein import The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ANXA7 APOA1 ATP5A1 ATP5C1 ATPAF1 ATPAF2 CDK4 CDKN1A FANCA GRB7 HMOX2 PIN1 PLG PSME3 RPP14 SMN1 SUMO4 TERT TK1 TRIM55 TRIM63 YWHAG	13 interactors: AIMP1 APP ATP5B ATP5C1 ATPAF1 ATPAF2 CSNK2A1 RPS6KB2 SHBG YWHAB YWHAG YWHAQ YWHAZ
Entrez ID		506	498
HPRD ID		00044	01258
Ensembl ID		ENSG00000110955	ENSG00000152234
Uniprot IDs		P06576	B4DY56 K7ENP3 P25705
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Organic Cyclic Compound Organ Regeneration Response To Steroid Hormone Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cell Cycle Arrest Mitochondrial ATP Synthesis Coupled Proton Transport Nucleoside Monophosphate Biosynthetic Process Response To Hormone Cellular Component Assembly Response To Organic Substance Response To Hyperoxia Response To Abiotic Stimulus Response To Glucocorticoid G1/S Transition Of Mitotic Cell Cycle Response To Stress ATP Synthesis Coupled Proton Transport Response To Corticosteroid Regulation Of Mitotic Cell Cycle Response To Toxic Substance Hemostasis ATP Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Response To Lipid Regulation Of Cell Cycle Process Cellular Metabolic Process Negative Regulation Of Cell Adhesion Molecule Production Fetal Process Involved In Parturition Negative Regulation Of Production Of SiRNA Involved In RNA Interference Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Response To Stimulus Regulation Of Cell Cycle Phase Transition DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of Cellular Protein Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Transferase Activity Positive Regulation Of Fibroblast Proliferation Regulation Of Body Fluid Levels Negative Regulation Of RNA Interference Skeletal Muscle Cell Proliferation Negative Regulation Of Interleukin-1 Beta Secretion Transcription, RNA-templated Platelet Degranulation Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Cell Aging	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Apoptotic Process Programmed Cell Death Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Establishment Of Localization In Cell Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Organelle Organization Protein Targeting Mitochondrial Transport Regulation Of Intracellular Transport Regulation Of Organelle Organization Cellular Localization ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Phosphorylation Chemotaxis Positive Regulation Of Cell Death Phosphate-containing Compound Metabolic Process Locomotion Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Defense Response Positive Regulation Of Transport Primary Spermatocyte Growth Regulation Of Protein Localization Regulation Of Apoptotic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Cellular Protein Metabolic Process Movement Of Cell Or Subcellular Component Membrane Organization Regulation Of Cell Death Developmental Cell Growth Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Protein Metabolic Process Axon Guidance Intracellular Protein Transport Synaptic Growth At Neuromuscular Junction Ribonucleoside Monophosphate Biosynthetic Process
Tagcloud ?		1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp c7orf10 candidate fhl5 fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide	2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Difference) ?		1p13 1p36 5x10 6q16 7p14 8q21 affecting ajap1 apoa1bp c7orf10 candidate fhl5 fut9 loci locus matched meta migraine mmp16 near poorly stat6 subgroup susceptibility tbc1d7 trait tspan2 understood wide	2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Intersection) ?