L1CAM and RDX

Number of citations of the paper that reports this interaction (PMID 12070130)
40

Data Source:
HPRD (in vivo)

		L1CAM	RDX
Gene Name		L1 cell adhesion molecule	radixin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Presynaptic Membrane Terminal Bouton	Ruffle Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Extrinsic Component Of Membrane Lamellipodium Filopodium T-tubule Cleavage Furrow Stereocilium Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Integrin Binding Sialic Acid Binding Identical Protein Binding Protein Self-association	Actin Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Chemotaxis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Blood Coagulation Positive Regulation Of Cell-cell Adhesion Cell-cell Adhesion Mediated By Integrin Homotypic Cell-cell Adhesion Positive Regulation Of Calcium-mediated Signaling Leukocyte Migration	Positive Regulation Of Gene Expression Microvillus Assembly Apical Protein Localization Actin Filament Capping Establishment Of Endothelial Barrier
Pathways		Interaction between L1 and Ankyrins Signal transduction by L1 Axon guidance L1CAM interactions Recycling pathway of L1 Basigin interactions Cell surface interactions at the vascular wall	Axon guidance L1CAM interactions Recycling pathway of L1
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ANK1 ANK2 CNTN1 CNTN2 CSNK2A1 EZR ITGA5 ITGAV MSN NCAM1 NCAN NRP1 NUMB PEA15 PRNP RABGEF1 RANBP9 RDX RPS6KA1 RPS6KA2 UBC	16 interactors: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1
Entrez ID		3897	5962
HPRD ID		02394	01534
Ensembl ID		ENSG00000198910	ENSG00000137710
Uniprot IDs		P32004	B0YJ88 P35241 Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cell Projection Organization Neuron Development Locomotion Cell Morphogenesis Cell Development Neuron Differentiation Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis Response To External Stimulus Cell Differentiation Nervous System Development Anatomical Structure Morphogenesis Anatomical Structure Development Regulation Of Cellular Component Organization Developmental Process System Development Multicellular Organismal Development Negative Regulation Of Apoptotic Process Endothelial Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Metabolic Process Negative Regulation Of Cell Death Endothelium Development Regulation Of Cellular Component Movement Regulation Of Apoptotic Process Response To Stimulus Establishment Of Endothelial Barrier Regulation Of Cell Death Cell Adhesion Regulation Of Protein Metabolic Process Membrane To Membrane Docking Negative Regulation Of Protein Metabolic Process Regulation Of Cell Migration Endothelial Cell Development Regulation Of Cellular Process Regulation Of Cell Motility Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway	Membrane To Membrane Docking Cellular Extravasation Negative Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Transmembrane Transport Rho Protein Signal Transduction Negative Regulation Of Sodium Ion Transmembrane Transport Single Organismal Cell-cell Adhesion Cellular Chemical Homeostasis Cell Surface Receptor Signaling Pathway Membrane Docking Negative Regulation Of Ion Transport Negative Regulation Of Sodium Ion Transport Regulation Of Proton Transport Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Regulation Of Locomotion Cell Adhesion Cellular Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Cellular Component Organization Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Response To Organonitrogen Compound Regulation Of Transmembrane Transporter Activity Negative Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Blood Coagulation Hemostasis Regulation Of Excretion Chemical Homeostasis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Regulation Of Cell Shape Cell-matrix Adhesion Cellular Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Sodium Ion Transmembrane Transporter Activity Nervous System Development Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		advocate androgen ar atlas bad cancers causally chip cohorts displaying endometrial exclusively find heterogeneous immuno inversely lysates mb436 overlaps precipitation preferentially progesterone serous similarities though tnbcs turn worst	amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody
Tagcloud (Difference) ?		advocate androgen ar atlas bad cancers causally chip cohorts displaying endometrial exclusively find heterogeneous immuno inversely lysates mb436 overlaps precipitation preferentially progesterone serous similarities though tnbcs turn worst	amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody
Tagcloud (Intersection) ?