SUMO4 and PDIA6

Number of citations of the paper that reports this interaction (PMID 16236267)
15

Data Source:
HPRD (in vivo)

		SUMO4	PDIA6
Gene Name		small ubiquitin-like modifier 4	protein disulfide isomerase family A, member 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function		Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Protein Sumoylation	Protein Folding Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Apoptotic Cell Clearance Cellular Protein Metabolic Process Cell Redox Homeostasis
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GNB2L1 GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1	9 interactors: ATP13A2 CASP8 CLN8 CSNK2A1 MTNR1A MTNR1B SLC2A4 SUMO4 VKORC1
Entrez ID		387082	10130
HPRD ID		10584	07504
Ensembl ID		ENSG00000177688	ENSG00000143870
Uniprot IDs		Q6EEV6	Q15084
PDB IDs			1X5D 3VWW 3W8J 4EF0 4GWR
Enriched GO Terms of Interacting Partners?		Protein Folding Regulation Of Cell Death Regulation Of Apoptotic Process Cellular Metabolic Process Response To Unfolded Protein Response To Stress Negative Regulation Of Cell Death 'de Novo' Protein Folding Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Toxin Transport Response To Organic Substance Nitrogen Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Metabolic Process Cellular Response To Stress Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Generation Of Precursor Metabolites And Energy Regulation Of Cellular Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Process Response To Reactive Oxygen Species Small Molecule Metabolic Process Organic Acid Metabolic Process Hydrogen Peroxide Catabolic Process Regulation Of Protein Metabolic Process Carboxylic Acid Metabolic Process Protein Refolding Endoplasmic Reticulum Unfolded Protein Response Ribonucleoside Monophosphate Biosynthetic Process Carbohydrate Biosynthetic Process Cellular Response To Organic Substance MRNA Metabolic Process Cellular Response To Unfolded Protein Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Nuclease Activity Nucleoside Monophosphate Biosynthetic Process Gluconeogenesis Monocarboxylic Acid Metabolic Process ER-nucleus Signaling Pathway Catabolic Process Ribose Phosphate Biosynthetic Process Apoptotic Process Biosynthetic Process Cellular Response To Topologically Incorrect Protein	Amylopectin Biosynthetic Process Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development L-glutamate Uptake Involved In Synaptic Transmission TRAIL-activated Apoptotic Signaling Pathway Response To Ethanol Response To Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Tagcloud ?		accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2	brains contributions cpg dysregulation epigenome excessive gpr3 h3k4me3 hairy hd hes4 htt huntington hypermethylation jagged2 lastly mapping mark mash1 methylated modifying neurodegeneration prefrontal shrna split striatal strikingly tmem106b trimethyl
Tagcloud (Difference) ?		accumulating behcet ccr1 ccr3 ccr6 cd40 ctla4 elucidating fcrl3 han helpful hopefully il17 il23r immunoregulatory irf5 l2 mcp multisystemic mystery opn predisposition profound ptpn22 regimes stat4 tgfbr3 tgrbr3 ubac2	brains contributions cpg dysregulation epigenome excessive gpr3 h3k4me3 hairy hd hes4 htt huntington hypermethylation jagged2 lastly mapping mark mash1 methylated modifying neurodegeneration prefrontal shrna split striatal strikingly tmem106b trimethyl
Tagcloud (Intersection) ?