KPNA3 and RPRD1A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KPNA3	RPRD1A
Gene Name		karyopherin alpha 3 (importin alpha 4)	regulation of nuclear pre-mRNA domain containing 1A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol	DNA-directed RNA Polymerase II, Holoenzyme
	Molecular Function	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Protein Transporter Activity
	Biological Process	Protein Complex Assembly NLS-bearing Protein Import Into Nucleus Cytokine-mediated Signaling Pathway Viral Entry Into Host Cell Viral Penetration Into Host Nucleus	Dephosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS		Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661)
Protein-Protein Interactions		28 interactors: APOL6 CDKN1B COIL DDX21 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 HNRNPC KPNB1 MAT2B MTA1 MVP MYOD1 NFE2L2 NFKB1 NUP50 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131	5 interactors: BCAR3 KDM1A KPNA3 RIOK2 YWHAZ
Entrez ID		3839	55197
HPRD ID		03536	10134
Ensembl ID		ENSG00000102753	ENSG00000141425
Uniprot IDs		O00505 Q8IYQ9	Q96P16
PDB IDs
Enriched GO Terms of Interacting Partners?		Viral Process RNA Metabolic Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Response To Stress Response To Organic Substance Nitrogen Compound Metabolic Process Gene Expression Nucleotide-excision Repair, DNA Damage Removal Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Apoptotic Process Termination Of RNA Polymerase I Transcription Programmed Cell Death Transcription Elongation From RNA Polymerase I Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process Osteoblast Differentiation Transcription Initiation From RNA Polymerase I Promoter Cell Death Death 7-methylguanosine MRNA Capping Response To Abiotic Stimulus Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Positive Regulation Of Metabolic Process Regulation Of Gene Expression Transcription-coupled Nucleotide-excision Repair Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Viral Transcription Positive Regulation Of Wound Healing Regulation Of Nucleic Acid-templated Transcription Cellular Response To DNA Damage Stimulus Regulation Of RNA Biosynthetic Process Response To Lipid Response To Estrogen Regulation Of Gene Expression, Epigenetic Negative Regulation Of Interleukin-12 Biosynthetic Process Nucleotide-excision Repair, DNA Duplex Unwinding Notochord Cell Development Regulation Of Cell Cycle Process Cellular Macromolecule Catabolic Process Macromolecule Biosynthetic Process	Regulation Of Primitive Erythrocyte Differentiation Viral Penetration Into Host Nucleus Golgi Reassembly Histamine Secretion By Mast Cell Establishment Of Golgi Localization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Golgi Inheritance Histone H3-K4 Demethylation Histamine Secretion Establishment Of Protein Localization To Organelle Positive Regulation Of Megakaryocyte Differentiation Histamine Transport Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Targeting Blood Coagulation Hemostasis Golgi Localization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Mast Cell Degranulation Response To Drug Protein Localization To Organelle Positive Regulation Of Erythrocyte Differentiation NLS-bearing Protein Import Into Nucleus Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Histone H3-K4 Methylation Mast Cell Mediated Immunity Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Body Fluid Levels Lysosome Localization Intracellular Transport Of Virus Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Wound Healing Mast Cell Activation Lens Morphogenesis In Camera-type Eye Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Hormone Metabolic Process Histone Lysine Demethylation
Tagcloud ?		alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Difference) ?		alpha4 ataxias capicua desensitize erk ets etv etv1 etv4 etv5 give highlight hmg importin interconnections mechanistic modulating motivating multisite nls p90 pea3 phosphorylations polyoma relieved represses rsk s6 spinocerebellar
Tagcloud (Intersection) ?