ARF1 and AP3D1

Number of citations of the paper that reports this interaction (PMID 11926829)
12

Data Source:
HPRD (in vitro, in vivo)

		ARF1	AP3D1
Gene Name		ADP-ribosylation factor 1	adaptor-related protein complex 3, delta 1 subunit
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Focal Adhesion Postsynaptic Density Sarcomere Neuron Projection Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane Membrane Coat Terminal Bouton
	Molecular Function	GTPase Activity Receptor Signaling Protein Activity Protein Binding GTP Binding Poly(A) RNA Binding	Transporter Activity
	Biological Process	Regulation Of Receptor Internalization Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Cellular Copper Ion Homeostasis Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Arp2/3 Complex-mediated Actin Nucleation Small Molecule Metabolic Process COPI Coating Of Golgi Vesicle Regulation Of Defense Response To Virus By Virus Long Term Synaptic Depression Membrane Organization Dendritic Spine Organization	Eye Pigment Biosynthetic Process Intracellular Protein Transport Anterograde Axon Cargo Transport Melanosome Organization Protein Localization To Organelle Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane
Pathways		Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Golgi Associated Vesicle Biogenesis Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Clathrin derived vesicle budding Lysosome Vesicle Biogenesis Golgi to ER Retrograde Transport MHC class II antigen presentation COPI Mediated Transport Phospholipid metabolism trans-Golgi Network Vesicle Budding Nef Mediated CD4 Down-regulation Adaptive Immune System PI Metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: AP1B1 AP1G1 AP3B1 AP3D1 AP3S2 AP4E1 AP4M1 ARFGAP1 ARFIP1 ARFIP2 ARHGAP21 ASAP1 ASAP2 CHRM3 COPB1 COPE COPG1 CYTH1 CYTH2 EEF1G GGA1 GGA2 GGA3 GOSR2 INSR KDELR1 MDM4 NOA1 NPM1 PICK1 PIP5K1A PLD1 PLD2 PLEKHA8 PLIN2 RALA TMED10 TMED2 TMEM106A WBP11	9 interactors: AP3S1 AP3S2 ARF1 ARF6 CTGF RUFY1 SLC30A3 VAMP7 VPS41
Entrez ID		375	8943
HPRD ID		00054	06260
Ensembl ID		ENSG00000143761	ENSG00000065000
Uniprot IDs		P84077	O14617
PDB IDs		1HUR 1RE0 1U81 3O47 4HMY	4AFI
Enriched GO Terms of Interacting Partners?		Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cellular Protein Localization Protein Localization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Golgi Vesicle Transport Localization Within Membrane Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Transport Establishment Of Organelle Localization Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Organelle Localization Vesicle Targeting Membrane Organization Membrane Budding Organelle Organization Regulation Of ARF Protein Signal Transduction Cytoplasmic Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity Synaptic Vesicle Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Golgi Localization Golgi To Vacuole Transport Regulation Of Ras Protein Signal Transduction Endosome To Melanosome Transport Cargo Loading Into Vesicle Pigment Granule Maturation Axon Cargo Transport Intra-Golgi Vesicle-mediated Transport Cellular Pigment Accumulation Cellular Pigmentation	Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Regulation Of Vesicle-mediated Transport Protein Localization Transport Cellular Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Anterograde Synaptic Vesicle Transport Regulation Of Endocytosis Anterograde Axon Cargo Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization Intracellular Transport Golgi Vesicle Transport Axon Cargo Transport Establishment Of Organelle Localization Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Actin Cytoskeleton Organization Organelle Fusion Regulation Of Actin Filament-based Process Regulation Of Protein Targeting To Vacuolar Membrane Vacuole Fusion, Non-autophagic Vacuolar Transport Organelle Localization Post-Golgi Vesicle-mediated Transport Regulation Of Cytoskeleton Organization Synaptic Vesicle Transport Organ Senescence Membrane Fusion Microtubule-based Transport Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Histamine Secretion By Mast Cell Triglyceride Transport Extracellular Matrix Constituent Secretion Eosinophil Degranulation Cytoskeleton-dependent Intracellular Transport Response To Anoxia Positive Regulation Of G0 To G1 Transition Movement Of Cell Or Subcellular Component Regulation Of Sequestering Of Zinc Ion Neutrophil Degranulation Positive Regulation Of Cardiac Muscle Contraction Positive Regulation Of Cytoskeleton Organization Vesicle Organization Myeloid Cell Apoptotic Process Regulation Of SNARE Complex Assembly
Tagcloud ?		adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Difference) ?		adp bulk close coated coatomer consumed contact copi dynamics endoplasmic exchange explored fission golgi governed gtpase interconnected maintain maintenance mitochondria mitochondrial powerhouse presumably produce proximity reticulum ribosylation thought vesicles	18s actb bestkeeper c2c12 cdc40 csnk2a2 dystrophic dystrophin exceptionally fbxo38 fbxw2 gapdh genorm h2k2b4 h2ksf1 htatsf1 informative mef2c myoblasts myod myogenesis myogenic myogenin normalization normalizing normfinder packages pak1ip1 zfp91
Tagcloud (Intersection) ?