IL7R and PTBP1

Number of citations of the paper that reports this interaction (PMID 23151878)
3

Data Source:
BioGRID (unspecified method)

		IL7R	PTBP1
Gene Name		interleukin 7 receptor	polypyrimidine tract binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome
	Molecular Function	Antigen Binding Interleukin-7 Receptor Activity Protein Binding	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of DNA Recombination Cell Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Immunoglobulin Production Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Size Positive Regulation Of Gene Expression Cell Growth T Cell Differentiation Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7-mediated Signaling Pathway B Cell Proliferation Lymph Node Development Homeostasis Of Number Of Cells	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation
Pathways		Signaling by Interleukins Interleukin-7 signaling Cytokine Signaling in Immune system	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Multiple sclerosis ( 21244703 19525953 21833088) Primary biliary cirrhosis ( 23000144 21399635) Type 1 diabetes ( 17554260) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		104 interactors: ALYREF CIRBP CPSF1 CRLF2 DDX21 DDX39B DDX3X DDX5 DHX36 DHX9 EIF2AK2 ELAVL1 EMG1 FAU FUS FYN G3BP1 GNB2L1 H1FX HIST1H1C HIST1H1E HIST2H2BE HNRNPA0 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPH3 HNRNPL HNRNPR HNRNPU HNRNPUL1 HNRNPUL2 IL2RG IL7 ILF2 ILF3 JAK1 JAK3 KIT LYN MAP4 NCL NONO PABPC1 PABPC4 PABPN1 PIK3R1 PTBP1 PTK2B PTMA PURA PURB QKI RAD21 RBM3 RBMX RPL15 RPL18 RPL22 RPL29 RPL30 RPL31 RPL6 RPL7 RPL8 RPS20 RPS3 RPSA RRAGA RSL1D1 SAFB SF1 SF3A1 SF3B1 SNRNP70 SNRPA SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP14 SRP9 SRSF3 SRSF9 SSB STAT3 STAT5A STAT5B SYNCRIP TOE1 TOP1 TSLP U2AF1 U2AF2 YBX1 YBX3 YWHAE YWHAG ZNF787	27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2
Entrez ID		3575	5725
HPRD ID		00893	02823
Ensembl ID		ENSG00000168685	ENSG00000011304
Uniprot IDs		D6RGV2 D9N160 P16871	P26599
PDB IDs		3DI2 3DI3 3UP1	1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Viral Process RNA Biosynthetic Process SRP-dependent Cotranslational Protein Targeting To Membrane Termination Of RNA Polymerase II Transcription Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Macromolecule Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Posttranscriptional Regulation Of Gene Expression MRNA Stabilization RNA 3'-end Processing MRNA 3'-end Processing RNA Catabolic Process Viral Transcription Cellular Metabolic Process Protein Targeting To Membrane DNA-templated Transcription, Termination Protein Targeting Nuclear-transcribed MRNA Catabolic Process Establishment Of Protein Localization To Organelle MRNA Catabolic Process Ribonucleoprotein Complex Assembly Regulation Of Translation Ribonucleoprotein Complex Biogenesis Biosynthetic Process Protein Localization To Organelle Translational Termination Establishment Of Protein Localization To Membrane Intracellular Transport Translational Elongation	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization
Tagcloud ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Intersection) ?