AMIGO2 and AMIGO3

Number of citations of the paper that reports this interaction (PMID 12629050)
18

Data Source:
HPRD (in vivo)

		AMIGO2	AMIGO3
Gene Name		adhesion molecule with Ig-like domain 2	adhesion molecule with Ig-like domain 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Brain Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Cell-cell Adhesion	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Brain Development Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS		Prostate cancer (gene x gene interaction) ( 22219177)	Ulcerative colitis ( 21297633)
Protein-Protein Interactions		3 interactors: AMIGO1 AMIGO3 CACNA1A	2 interactors: AMIGO1 AMIGO2
Entrez ID		347902	386724
HPRD ID		16483	16484
Ensembl ID		ENSG00000139211	ENSG00000176020
Uniprot IDs		Q86SJ2	Q86WK7
PDB IDs
Enriched GO Terms of Interacting Partners?		Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Brain Development Head Development Central Nervous System Development Cerebellar Molecular Layer Development Regulation Of Axonogenesis Vestibular Nucleus Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Musculoskeletal Movement, Spinal Reflex Action Cerebellum Maturation Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Regulation Of Neuron Projection Development Nervous System Development Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Negative Regulation Of Hormone Biosynthetic Process Pons Development Regulation Of Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Cerebellar Purkinje Cell Differentiation Organ Development Neuron Projection Morphogenesis Cerebellar Purkinje Cell Layer Morphogenesis Regulation Of Neurogenesis Reflex Cell Morphogenesis Involved In Differentiation Behavioral Response To Pain Neuromuscular Synaptic Transmission Axonal Fasciculation Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neuron Projection Development Neurotransmitter Metabolic Process Cell Projection Morphogenesis Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Regulation Of Cell Development Cell Part Morphogenesis Calcium Ion Import Regulation Of Hormone Metabolic Process Cerebellar Purkinje Cell Layer Development Membrane Depolarization During Action Potential Neuron Recognition	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Brain Development Head Development Central Nervous System Development Axonal Fasciculation Cell Adhesion Neuron Recognition Positive Regulation Of Axonogenesis
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