ID2 and TSTA3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ID2	TSTA3
Gene Name		inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	tissue specific transplantation antigen P35B
Image
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Microtubule Cytoskeleton Protein Complex	Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Ion Channel Binding Protein Dimerization Activity	Electron Carrier Activity Isomerase Activity GDP-4-dehydro-D-rhamnose Reductase Activity GDP-L-fucose Synthase Activity Coenzyme Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Natural Killer Cell Differentiation Membranous Septum Morphogenesis Bundle Of His Development Transcription, DNA-templated Multicellular Organismal Development Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Regulation Of Lipid Metabolic Process Olfactory Bulb Development Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Enucleate Erythrocyte Differentiation Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Locomotor Rhythm Negative Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Macrophage Differentiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Maturation Peyer's Patch Development Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Adipose Tissue Development Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Neural Precursor Cell Proliferation	Leukocyte Cell-cell Adhesion GDP-mannose Metabolic Process Cytolysis 'de Novo' GDP-L-fucose Biosynthetic Process Oxidation-reduction Process
Pathways
Drugs			NADH
Diseases
GWAS		IgE levels ( 22075330)	Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		37 interactors: ADD1 ASB4 CDK2 ELK1 ELK3 ELK4 GATA4 HES1 HSPA5 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 PAX2 PAX5 PAX8 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TSTA3 UNC119	3 interactors: ID2 NEDD4 RIOK2
Entrez ID		3398	7264
HPRD ID		02664	00654
Ensembl ID		ENSG00000115738	ENSG00000104522
Uniprot IDs		Q02363 Q53T66	Q13630
PDB IDs		4AYA	4B8W 4B8Z 4BKP 4E5Y
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Muscle Structure Development Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cell Differentiation Cell Differentiation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Muscle Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Organ Development Positive Regulation Of Skeletal Muscle Fiber Development Skeletal Muscle Cell Differentiation Cell Fate Commitment Developmental Process Regulation Of Cellular Process Chromatin Modification Tissue Development Skeletal Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Heart Morphogenesis Bundle Of His Development Endodermal Digestive Tract Morphogenesis Response To Metal Ion Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Response To Light Stimulus Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Lymphocyte Activation Negative Regulation Of B Cell Differentiation Membranous Septum Morphogenesis Glucocorticoid Receptor Signaling Pathway Response To Radiation Locomotor Rhythm Response To Inorganic Substance Positive Regulation Of Astrocyte Differentiation Leukocyte Activation Heart Development Positive Regulation Of Macrophage Differentiation Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Neuron Differentiation Cardiac Conduction System Development Protein Localization To Lysosome Enucleate Erythrocyte Differentiation Cellular Response To Lithium Ion Circadian Behavior Peyer's Patch Development Rhythmic Behavior Cell Activation Receptor Catabolic Process Positive Regulation Of Erythrocyte Differentiation Natural Killer Cell Differentiation Regulation Of Neurogenesis Negative Regulation Of Oligodendrocyte Differentiation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Targeting To Vacuole Mammary Gland Epithelial Cell Proliferation Entrainment Of Circadian Clock By Photoperiod Mammary Gland Epithelial Cell Differentiation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Establishment Of Protein Localization To Vacuole Photoperiodism Entrainment Of Circadian Clock
Tagcloud ?		basic bhlh blackfan broadly compensated competed dba declined defect diamond disrupted downregulate e47 enhancing erythroblasts erythroid globin heb helix heterodimer maturation positively precursors progenitors scf scl sequesters stimulates transfusion
Tagcloud (Difference) ?		basic bhlh blackfan broadly compensated competed dba declined defect diamond disrupted downregulate e47 enhancing erythroblasts erythroid globin heb helix heterodimer maturation positively precursors progenitors scf scl sequesters stimulates transfusion
Tagcloud (Intersection) ?